Browsing Externally hosted open access publications with University of Galway authors (2) by Subject "il-1"
Now showing items 1-2 of 2
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Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome
(BMJ, 2016-07-29)Objective To explore whether gene expression profiling can identify a molecular mechanism for the clinical benefit of canakinumab treatment in patents with tumour necrosis factor receptor-associated periodic syndrome ... -
The monoacylglycerol lipase inhibitor jzl184 attenuates lps-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action
(Wiley-Blackwell, 2013-05-27)Background and purpose JZL184 is a selective inhibitor of monoacylglycerol lipase (MAGL), the enzyme that preferentially catabolizes the endocannabinoid 2-arachidonoyl glycerol (2-AG). Here, we have studied the effects of ...