Browsing Externally hosted open access publications with University of Galway authors (2) by Title
Now showing items 3744-3763 of 4432
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Tardigrada of ireland: a review of records and an updated checklist of species including a new addition to the irish fauna
(Pensoft Publishers, 2016-09-12)The phylum Tardigrada was not recorded in Ireland until the Clare Island Survey of 1909-1911, with only rare subsequent reports on Irish tardigrade species. In recent decades, significant taxonomic revision has occurred ... -
Targeted next-generation sequencing of familial platelet disorder with predisposition to acute myeloid leukaemia
(Wiley-Blackwell, 2015-11-03) -
Targeted resequencing of the micrornaome and 3′utrome reveals functional germline dna variants with altered prevalence in epithelial ovarian cancer
(Springer Nature, 2014-06-09)Ovarian cancer is a major cause of cancer deaths, yet there have been few known genetic risk factors identified, the best known of which are disruptions in protein coding sequences (BRCA1 and 2). Recent findings indicate ... -
Targeting aml through dr4 with a novel variant of rhtrail
(Wiley-Blackwell, 2011-09-26)Despite progress in the treatment of acute myelogenous leukaemia (AML) the outcome often remains poor. Tumour necrosis factor related apoptosis-inducing ligand (TRAIL) is a promising therapeutic agent in many different ... -
Targeting cancer using kat inhibitors to mimic lethal knockouts
(Portland Press Ltd., 2016-08-15)Two opposing enzyme classes regulate fundamental elements of genome maintenance, gene regulation and metabolism, either through addition of an acetyl moiety by histone acetyltransferases (HATs) or its removal by histone ... -
Targeting delivery in parkinson's disease
(Elsevier BV, 2016-08-01)Disease-modifying therapies for Parkinson's disease (PD), with the potential to halt the neurodegenerative process and to stimulate the protection, repair, and regeneration of dopaminergic neurons, remain a vital but unmet ... -
Targeting egfr with photodynamic therapy in combination with erbitux enhances in vivo bladder tumor response
(Springer Nature, 2009-01-01)Background: Photodynamic therapy (PDT) is a promising cancer treatment modality that involves the interaction of the photosensitizer, molecular oxygen and light of specific wavelength to destroy tumor cells. Treatment ... -
Targeting of xiap combined with systemic mesenchymal stem cell-mediated delivery of strail ligand inhibits metastatic growth of pancreatic carcinoma cells
(Wiley-Blackwell, 2010-11-01)Disseminating tumors are one of the gravest medical problems. Here, we combine the tumor-specific apoptosis-inducing activity of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with the ability of mesenchymal ... -
Targeting selectins and their ligands in cancer
(Frontiers Media SA, 2016-04-18)Aberrant glycosylation is a hallmark of cancer cells with increased evidence pointing to a role in tumor progression. In particular, aberrant sialylation of glycoproteins and glycolipids has been linked to increased immune ... -
Targeting the ep1 receptor reduces fas ligand expression and increases the antitumor immune response in anin vivomodel of colon cancer
(Wiley-Blackwell, 2013-03-04)Despite studies demonstrating that inhibition of cyclooxygenase-2 (COX-2)-derived prostaglandin E2 (PGE2) has significant chemotherapeutic benefits in vitro and in vivo, inhibition of COX enzymes is associated with serious ... -
Targeting the fms-like tyrosine kinase 3 in acute myeloid leukemia
(Springer Nature, 2012-04-27)Acute myeloid leukemia (AML) is a highly heterogenous disease with multiple signaling pathways contributing to its pathogenesis. A key driver of AML is the FMS-like tyrosine kinase receptor-3 (FLT3). Activating mutations ... -
Targeting the pim kinases in multiple myeloma
(Springer Nature, 2015-07-17)Multiple myeloma (MM) is a plasma cell malignancy that remains incurable. Novel treatment strategies to improve survival are urgently required. The Pims are a small family of serine/threonine kinases with increased expression ... -
Taxonomy and nomenclature of the conjugatophyceae (= zygnematophyceae)
(The Korean Society of Phycology, 2013-03-15)The conjugating algae, an almost exclusively freshwater and extraordinarily diverse group of streptophyte green algae, are referred to a class generally known as the Conjugatophyceae in Central Europe and the Zygnematophyceae ... -
“tá cuid de na mná blasta/some women are sweet talkers”: representations of women in seán ó heochaidh’s field diaries for the irish folklore commission
(Estudios Irlandeses, 2017-10-30)This article discusses representations of women in diaries written by Sean O hEochaidh as part of his work as a field collector for the Irish Folklore Commission (1935-1971). Focusing on a number of well-described events ... -
Tct-106 bioinnovate ireland: a multidisciplinary approach to medical device innovation
(Elsevier BV, 2012-10-01) -
Tct-206 a pilot study on renal sympathetic denervation for resistant hypertension in the west of ireland
(Elsevier BV, 2012-10-01) -
Tct-439 assessment of biocompatibility of the multilayer flow modulator with varying thread numbers
(Elsevier BV, 2014-09-01) -
Tct-446 treatment of rabbit aneurysms with the intracranial multilayer flow modulator
(Elsevier BV, 2014-09-01)