Browsing Externally hosted open access publications with University of Galway authors (2) by Title
Now showing items 1352-1371 of 4432
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Effects and mechanisms of action of sildenafil citrate in human chorionic arteries
(Springer Nature, 2009-01-01)Objectives: Sildenafil citrate, a specific phosphodiesterase-5 inhibitor, is increasingly used for pulmonary hypertension in pregnancy. Sildenafil is also emerging as a potential candidate for the treatment of intra-uterine ... -
Effects of a novel schizophrenia risk variant rs7914558 at cnnm2 on brain structure and attributional style
(Royal College of Psychiatrists, 2013-12-05)Background A single nucleotide polymorphism (rs7914558) within the cyclin M2 (CNNM2) gene was recently identified as a common risk variant for schizophrenia. The mechanism by which CNNM2 confers risk is unknown. Aims To ... -
Effects of abnormal cannabidiol on oxytocin-induced myometrial contractility
(BioScientifica, 2010-01-12)The objective of this study was to investigate the effects of abnormal cannabidiol (abn-cbd) on oxytocin-induced myometrial contractility occurring during pregnancy. Isometric tension recordings were performed in isolated ... -
Effects of age on the detection and management of breast cancer
(MDPI AG, 2015-05-22)Currently, breast cancer affects approximately 12% of women worldwide. While the incidence of breast cancer rises with age, a younger age at diagnosis is linked to increased mortality. We discuss age related factors affecting ... -
Effects of air embolism size and location on porcine hepatic microcirculation in machine perfusion
(Wiley-Blackwell, 2014-04-25) -
Effects of an eight-week supervised, structured lifestyle modification programme on anthropometric, metabolic and cardiovascular risk factors in severely obese adults
(Springer Nature, 2015-08-01)Background: Lifestyle modification is fundamental to obesity treatment, but few studies have described the effects of structured lifestyle programmes specifically in bariatric patients. We sought to describe changes in ... -
Effects of arterial cannulation stress on regional cerebral blood flow in major depressive disorder
(Springer Nature, 2012-03-08)Individuals with major depressive disorder (MDD) display abnormal neurophysiological responses to psychological stress but little is known about their neurophysiological responses to physiological stressors. Using [O-15]-H2O ... -
Effects of combined progesterone and 17β-estradiol treatment on the transcriptome of cultured human myometrial smooth muscle cells
(American Physiological Society, 2015-11-03)A transcriptomic analysis of cultured human uterine smooth muscle cells (hUtSMCs) was performed to examine gene expression profiles in smooth muscle in an environment containing the two major steroid hormones that regulate ... -
Effects of exercise on alterations in redox homeostasis in elite male and female endurance athletes using a clinical point-of-care test
(Canadian Science Publishing, 2016-10-01)Exercise causes alterations in redox homeostasis (ARH). Measuring ARH in elite athletes may aid in the identification of training tolerance, fatigued states, and underperformance. To the best of our knowledge, no studies ... -
Effects of fibroglandular tissue distribution on data-independent beamforming algorithms
(EMW Publishing, 2009-01-01)The effects of the fibroglandular tissue distribution of the breast on data-independent microwave imaging algorithms are investigated in this paper. A data-independent beamformer is a beamformer whose weights do not depend ... -
Effects of growth phase and temperature onσbactivity within alisteria monocytogenespopulation: evidence for rsbv-independent activation ofσbat refrigeration temperatures
(Hindawi Limited, 2014-01-01)The alternative sigma factor sigma(B) of Listeria monocytogenes is responsible for regulating the transcription of many of the genes necessary for adaptation to both food-related stresses and to conditions found within the ... -
Effects of heating on proportions of azaspiracids 1–10 in mussels (mytilus edulis) and identification of carboxylated precursors for azaspiracids 5, 10, 13, and 15
(American Chemical Society (ACS), 2015-12-30)Azaspiracids (AZAs) are marine biotoxins that induce human illness following the consumption of contaminated shellfish. European Union regulation stipulates that only raw shellfish are tested, yet shellfish are often cooked ... -
Effects of in vitro endochondral priming and pre-vascularisation of human msc cellular aggregates in vivo
(Springer Nature, 2015-11-05)Introduction: During endochondral ossification, both the production of a cartilage template and the subsequent vascularisation of that template are essential precursors to bone tissue formation. Recent studies have found ... -
Effects of increasing levothyroxine on pregnancy outcomes in women with uncontrolled hypothyroidism
(Wiley-Blackwell, 2016-08-23)Objective Uncontrolled hypothyroidism has been associated with an increased risk of adverse pregnancy outcomes. We aimed to assess the effectiveness of increasing levothyroxine (LT4) dose on reducing the risk of adverse ... -
Effects of interventions promoting monitoring of medication use and brief messaging on medication adherence for people with type 2 diabetes: a systematic review of randomized trials
(Wiley-Blackwell, 2015-11-17)AimsTo assess the impact of interventions promoting the monitoring of medication use and brief messaging to support medication adherence in patients with Type 2 diabetes mellitus, and to investigate the extent of theory ... -
Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury
(Ovid Technologies (Wolters Kluwer Health), 2013-04-01)Background: Mesenchymal stromal cells (MSCs) have been demonstrated to attenuate acute lung injury when delivered by intravenous or intratracheal routes. The authors aimed to determine the efficacy of and mechanism of ... -
Effects of levothyroxine therapy on pregnancy outcomes in women with subclinical hypothyroidism
(Mary Ann Liebert Inc, 2016-07-01)Background: Subclinical hypothyroidism (SCH) has been associated with increased risk of adverse pregnancy outcomes in some, but not all, studies. Uncertainty remains regarding the impact of levothyroxine (LT4) therapy on ... -
Effects of long-term exposure of gelatinated and non-gelatinated cadmium telluride quantum dots on differentiated pc12 cells
(Springer Nature, 2012-01-01)Background: The inherent toxicity of unmodified Quantum Dots (QDs) is a major hindrance to their use in biological applications. To make them more potent as neuroprosthetic and neurotherapeutic agents, thioglycolic acid ... -
Effects of mir137 on fronto-amygdala functional connectivity
(Elsevier BV, 2014-04-01)