Browsing Externally hosted open access publications with University of Galway authors (2) by Title
Now showing items 698-717 of 4432
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C-jun n-terminal kinase-mediated rad18 phosphorylation facilitates pol recruitment to stalled replication forks
(American Society for Cell Biology (ASCB), 2012-03-28)The E3 ubiquitin ligase Rad18 chaperones DNA polymerase eta (Pol eta) to sites of UV-induced DNA damage and monoubiquitinates proliferating cell nuclear antigen (PCNA), facilitating engagement of Pol eta with stalled ... -
C-nap1 and rootletin restrain dna damage-induced centriole splitting and facilitate ciliogenesis
(Informa UK Limited, 2012-10-15)Cilia are found on most human cells and exist as motile cilia or non-motile primary cilia. Primary cilia play sensory roles in transducing various extracellular signals, and defective ciliary functions are involved in a ... -
$c^{\alpha}$-hölder classical solutions for non-autonomous neutral differential equations
(American Institute of Mathematical Sciences (AIMS), 2010-09-01)In this paper we discuss the existence of alpha-Holder classical solutions for non-autonomous abstract partial neutral functional differential equations. An application is considered. -
Calcium-binding capacity of centrin2 is required for linear poc5 assembly but not for nucleotide excision repair
(Public Library of Science (PLoS), 2013-07-02)Centrosomes, the principal microtubule-organising centres in animal cells, contain centrins, small, conserved calcium-binding proteins unique to eukaryotes. Centrin2 binds to xeroderma pigmentosum group C protein (XPC), ... -
Calculation of leakage inductance for high-frequency transformers
(Institute of Electrical and Electronics Engineers (IEEE), 2015-10-01)Frequency-dependent leakage inductance is often observed. The high-frequency eddy current effects cause a reduction in leakage inductance. The proximity effect between adjacent layers is responsible for the reduction of ... -
Caliop near-real-time backscatter products compared to earlinet data
(Copernicus GmbH, 2015-11-03)The expedited near-real-time Level 1.5 Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) version 3 products were evaluated against data from the ground-based European Aerosol Research Lidar Network (EARLINET). The ... -
Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination
(Springer Nature, 2013-01-01)Background: Calreticulin (CRT) is a chaperone protein, which aids correct folding of glycosylated proteins in the endoplasmic reticulum (ER). Under conditions of ER stress, CRT is upregulated and may be displayed on the ... -
Can 'permissive' hypercapnia modulate the severity of sepsis-induced ali/ards?
(Springer Nature, 2011-01-01) -
Can a young muscle's stem cell secretome prolong our lives?
(Springer Nature, 2012-01-01)Ageing is a biological certainty for all living organisms, and is due to the loss of tissue homeostasis and regenerative capacity (except for newts) in which somatic stem cells are thought to play an important role. Many ... -
Can biosecurity and local network properties predict pathogen species richness in the salmonid industry?
(Public Library of Science (PLoS), 2018-01-30)Salmonid farming in Ireland is mostly organic, which implies limited disease treatment options. This highlights the importance of biosecurity for preventing the introduction and spread of infectious agents. Similarly, the ... -
Can the observance of human rights of individuals enhance their resilience to cope with natural disasters?
(Elsevier BV, 2014-01-01) -
Can the onset of type 2 diabetes be delayed by a group-based lifestyle intervention in women with prediabetes following gestational diabetes mellitus (gdm)? findings from a randomized control mixed methods trial
(Hindawi Limited, 2015-01-01)Objective. To evaluate a 12-week group-based lifestyle intervention programme for women with prediabetes following gestational diabetes (GDM). Design. A two-group, mixed methods randomized controlled trial in which 50 women ... -
Can voluntary workplace partnership deliver sustainable mutual gains?
(Wiley-Blackwell, 2009-09-01)This article draws on two Irish case studies to examine the nature and outcomes of voluntary workplace partnership (WP), and the conditions affecting its durability. We found that WP delivered mutual gains for all stakeholders ... -
Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome
(BMJ, 2016-07-29)Objective To explore whether gene expression profiling can identify a molecular mechanism for the clinical benefit of canakinumab treatment in patents with tumour necrosis factor receptor-associated periodic syndrome ... -
Canakinumab treatment for patients with active recurrent or chronic tnf receptor-associated periodic syndrome (traps): an open-label, phase ii study
(BMJ, 2016-06-07)Objective To evaluate the efficacy of canakinumab, a high-affinity human monoclonal anti-interleukin-1 beta antibody, in inducing complete or almost complete responses in patients with active tumour necrosis factor ... -
Cancer diagnostics via ultrasensitive multiplexed detection of parathyroid hormone-related peptides with a microfluidic immunoarray
(American Chemical Society (ACS), 2016-09-20)Parathyroid, hormone-related peptide (PTHrP) is recognized as the-Major causative agent of humoral hypercalcemia of malignancy (HHM). The paraneoplastic PTHrP has also been implicated in tumor progression and metastasis ... -
Cancer-related fatigue in post-treatment cancer survivors: application of the common sense model of illness representations
(Springer Nature, 2016-11-25)Background: Cancer-related fatigue (CrF) is a common and disruptive symptom that may be experienced during and after cancer. Research into the subjective experience of fatigue in this group is required. The common sense ... -
Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer
(Informa UK Limited, 2011-02-15)Inducible nitric oxide synthase (NOS2) is an inflammation responsive enzyme (EC 1.14.13.39) that is induced during acute and chronic inflammation and tissue injury as part of the host defense and wound healing process. ... -
Cannabinoids: clearing the smoke on pain, inflammation and neurodegeneration
(Wiley-Blackwell, 2014-03-01)Linked ArticlesThis article is part of a themed section on Cannabinoids 2013. To view the other articles in this section, see Fagan and Campbell (2014) DOI: , Ignatowska-Jankowska etal. (2014) DOI: , Ligresti etal. (2014) ...