Browsing by Subject "myelin"
Now showing items 1-3 of 3
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Development of a mixed glial in vitro robust platform for therapeutic applications in spinal cord injury
(NUI Galway, 2021-06-30)Spinal cord injury (SCI) is a catastrophic event, and current strategies for SCI pose several limitations. One of the critical hallmarks of SCI is inflammation, which is due to the activation of microglia and astrocytes. ... -
Endoplasmic reticulum stress signalling in myelination
(2017-12-07)Demyelinating conditions such as multiple sclerosis have a continued unmet need for remyelinating therapies. Myelin is a multi-lamellar membrane structure made by oligodendrocyte progenitor cells (OPCs) that is critical ... -
The structural and functional role of myelin fast-migrating cerebrosides: pathological importance in multiple sclerosis
(Future Medicine Ltd, 2011-04-01)A family of neutral glycosphingolipids containing a 3-O-acetyl-sphingosine galactosylceramide (3-SAG) has been characterized. Seven new derivatives of galactosylceramide (GalCer), designated as fast-migrating cerebrosides ...