Browsing by Subject "extracellular-matrix"
Now showing items 1-8 of 8
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Adipose-derived stem cells in novel approaches to breast reconstruction: their suitability for tissue engineering and oncological safety
(SAGE Publications, 2017-08-16)Adipose-derived stem cells (ADSCs) are rapidly becoming the gold standard cell source for tissue engineering strategies and hold great potential for novel breast reconstruction strategies. However, their use in patients ... -
Biomaterial-enhanced cell and drug delivery: lessons learned in the cardiac field and future perspectives
(Wiley-Blackwell, 2016-02-03)Heart failure is a significant clinical issue. It is the cause of enormous healthcare costs worldwide and results in significant morbidity and mortality. Cardiac regenerative therapy has progressed considerably from clinical ... -
Fibrillin-1 in incisional hernias: an immunohistochemical study in scar and non-scar regions of human skin and muscle fasciae
(Wiley-Blackwell, 2008-05-01)Incisional hernias represent one of the most common complications after laparotomy. Specific pre-operative risk factors have not yet been identified. Recent studies indicate that changes in extracellular matrix components ... -
Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - a step closer to physiologically relevant in vitro organogenesis
(Springer Nature, 2016-08-01)Modular tissue engineering is based on the cells' innate ability to create bottom-up supramolecular assemblies with efficiency and efficacy still unmatched by man-made devices. Although the regenerative potential of such ... -
Mesenchymal chondroprogenitor cell origin and therapeutic potential
(Springer Nature, 2011-01-01)Mesenchymal progenitor cells, a multipotent adult stem cell population, have the ability to differentiate into cells of connective tissue lineages, including fat, cartilage, bone and muscle, and therefore generate a great ... -
Three dimensional honeycomb patterned fibrinogen based nanofibers induce substantial osteogenic response of mesenchymal stem cells
(Springer Nature, 2017-11-21)Stem cells therapy offers a viable alternative for treatment of bone disorders to the conventional bone grafting. However clinical therapies are still hindered by the insufficient knowledge on the conditions that maximize ... -
Towards in vitro vascularisation of collagen-gag scaffolds
(ECM Research Journal, 2011-01-12)Collagen-glycosaminoglycan scaffolds that have been used clinically for skin regeneration have also shown significant promise for other applications in tissue engineering. However, regeneration of thicker tissues with the ... -
Unique glycosignature for intervertebral disc and articular cartilage cells and tissues in immaturity and maturity
(Springer Nature, 2016-03-11)In this study, on/off markers for intervertebral disc (IVD) and articular cartilage (AC) cells (chondrocytes) and distinct glycoprofiles of cell and tissue-types were identified from immaturity to maturity. Three and eleven ...