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Now showing items 6373-6392 of 14646
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Human mesenchymal stromal cells broadly modulate high glucose-induced inflammatory responses of renal proximal tubular cell monolayers
(BMC, 2019-11-19)Background: Renal proximal tubular epithelial cells (RPTEC) are dysfunctional in diabetic kidney disease (DKD). Mesenchymal stromal cells (MSC) may modulate DKD pathogenesis through anti-inflammatory mediators. This study ... -
Human metapneumovirus-associated respiratory tract infections in the republic of ireland during the influenza season of 2003–2004
(Elsevier BV, 2005-05-01)Human metapneumovirus (hMPV) is a newly identified paramyxovirus that has been associated with respiratory tract illness in children aged < 5 years, the elderly, and immunocompromised patients. This study determined the ... -
Human monocyte subset distinctions and function: Insights from gene expression analysis
(Frontiers Media, 2020-06-04)Monocytes are a highly plastic innate immune cell population that displays significant heterogeneity within the circulation. Distinct patterns of surface marker expression have become accepted as a basis for distinguishing ... -
Human replication protein a
(American Society for Biochemistry & Molecular Biology (ASBMB), 2003-02-24)Although the mechanical aspects of the single-stranded DNA (ssDNA) binding activity of human replication protein A (RPA) have been extensively studied, only limited information is available about its interaction with other ... -
Human Resource Development in Multinational Organisations: Introductory Forward to Special Issue
(2013)[no abstract available] -
Human rights and foreign investment
(2015-03-27)This study details the mechanisms of a neoliberal ideology operative in the current international approach to foreign direct investment (FDI). It charts an increasing dependency on FDI within the process of international ... -
Human rights and smart economics: Mainstreaming gender in international trade policy
(UCD Law Review, 2009)At the time, the 1995 Fourth World Conference on Women in Beijing was applauded as a massive turning point for the status of women's human rights worldwide. Gender mainstreaming, established in the Beijing Platform for ... -
Human rights compliant decision-making in child protection: Lessons for Ireland from a comparative socio-legal case study analysis of Ireland, England and Germany
(NUI Galway, 2021-08-01)Children have a right to be protected from harm and the State is obliged to take measures to vindicate that right. The State may intervene in family life by restricting parental rights, removing a child into care or placing ... -
A human rights framework: Background Research for the Truth Recovery Design Process
(Truth Recovery Design Panel, 2021-09-27)[No abstract available] -
The Human Rights Triangle: Transnational Corporations, International Human Law and Regional Cooperation in the Context of Development
(2013-01-29)Following World War II, the allied powers sought to improve global financial stability and ensure that basic rights were codified and protected at the international level. The UN Charter and the Bretton Woods agreements ... -
Human stem cell delivery for treatment of large segmental bone defects
(Proceedings of the National Academy of Sciences, 2010-01-19)Local or systemic stem cell delivery has the potential to promote repair of a variety of damaged or degenerated tissues. Although various stem cell sources have been investigated for bone repair, few comparative reports ... -
Human stem cell modeling for amyotrophic lateral sclerosis
(NUI Galway, 2022-09-28)Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs). Most ALS cases are sporadic, with no family history or known genetic ... -
Human stem cell modelling for heart disease of long QT syndrome
(NUI Galway, 2022-04-29)Sudden cardiac death (SCD) in otherwise healthy young people is a public health priority. Long QT syndrome (LQTS) is the commonest life-threatening cardiac arrhythmia contributing to SCD under 40 years old with an estimated ... -
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
(Springer Nature, 2016-10-13)The two hemispheres of the human brain differ functionally and structurally. Despite over a century of research, the extent to which brain asymmetry is influenced by sex, handedness, age, and genetic factors is still ... -
Human trafficking and China: Past and present
(2014-06)The idea of human trafficking as a new and distinct problem, a modern form of slavery that entraps individuals without agency in their own countries and abroad, is a common perception that has popularised the usage of the ... -
Human uterine lower segment myometrial cell and nuclear volume at term: influence of maternal age
(Wiley-Blackwell, 2014-09-29)Little is known about the cytoarchitecture of human myometrial cells in pregnancy, and whether or not this may be influenced by maternal characteristics such as age, parity and body mass index (BMI). The aim of this study ... -
A human-centered design of a connected health system for older adults
(2017-08-15)The work outlined in this thesis explores the design of Connected Health devices, analyses the user characteristics of older adults and suggests a design methodology which was then applied to the design of two elements ...