Browsing by Title
Now showing items 6369-6388 of 14647
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Human endogenous retrovirus k and cancer: innocent bystander or tumorigenic accomplice?
(Wiley-Blackwell, 2014-06-17)Harbored as relics of ancient germline infections, human endogenous retroviruses (HERVs) now constitute up to 8% of our genome. A proportion of this sequence has been co-opted for molecular and cellular processes, beneficial ... -
Human enhancement, social solidarity and the distribution of responsibility
(Springer Nature, 2015-07-29)This paper tries to clarify, strengthen and respond to two prominent objections to the development and use of human enhancement technologies. Both objections express concerns about the link between enhancement and the drive ... -
Human Flourishing: The Grounds of Moral Judgment
(Springer, 2008) -
Human induced pluripotent stem cells as a model for neurodevelopmental disease
(2015-10-01)Abstract Autism spectrum disorders (ASD) are neurodevelopmental disorders which encompass a wide range of symptoms, including intellectual disability and delayed development, while the phenotype can range from mild to ... -
Human induced pluripotent stem cells as an in vitro model for autism spectrum disorder
(NUI Galway, 2022-08-23)Autism spectrum disorders (ASD) are neurodevelopmental disorders which encompass a wide range of symptoms, including intellectual disability and delayed development, while the phenotype can range from mild to severe. Genetic ... -
Human mesenchymal stromal cells broadly modulate high glucose-induced inflammatory responses of renal proximal tubular cell monolayers
(BMC, 2019-11-19)Background: Renal proximal tubular epithelial cells (RPTEC) are dysfunctional in diabetic kidney disease (DKD). Mesenchymal stromal cells (MSC) may modulate DKD pathogenesis through anti-inflammatory mediators. This study ... -
Human metapneumovirus-associated respiratory tract infections in the republic of ireland during the influenza season of 2003–2004
(Elsevier BV, 2005-05-01)Human metapneumovirus (hMPV) is a newly identified paramyxovirus that has been associated with respiratory tract illness in children aged < 5 years, the elderly, and immunocompromised patients. This study determined the ... -
Human monocyte subset distinctions and function: Insights from gene expression analysis
(Frontiers Media, 2020-06-04)Monocytes are a highly plastic innate immune cell population that displays significant heterogeneity within the circulation. Distinct patterns of surface marker expression have become accepted as a basis for distinguishing ... -
Human replication protein a
(American Society for Biochemistry & Molecular Biology (ASBMB), 2003-02-24)Although the mechanical aspects of the single-stranded DNA (ssDNA) binding activity of human replication protein A (RPA) have been extensively studied, only limited information is available about its interaction with other ... -
Human Resource Development in Multinational Organisations: Introductory Forward to Special Issue
(2013)[no abstract available] -
Human rights and foreign investment
(2015-03-27)This study details the mechanisms of a neoliberal ideology operative in the current international approach to foreign direct investment (FDI). It charts an increasing dependency on FDI within the process of international ... -
Human rights and smart economics: Mainstreaming gender in international trade policy
(UCD Law Review, 2009)At the time, the 1995 Fourth World Conference on Women in Beijing was applauded as a massive turning point for the status of women's human rights worldwide. Gender mainstreaming, established in the Beijing Platform for ... -
Human rights compliant decision-making in child protection: Lessons for Ireland from a comparative socio-legal case study analysis of Ireland, England and Germany
(NUI Galway, 2021-08-01)Children have a right to be protected from harm and the State is obliged to take measures to vindicate that right. The State may intervene in family life by restricting parental rights, removing a child into care or placing ... -
A human rights framework: Background Research for the Truth Recovery Design Process
(Truth Recovery Design Panel, 2021-09-27)[No abstract available] -
The Human Rights Triangle: Transnational Corporations, International Human Law and Regional Cooperation in the Context of Development
(2013-01-29)Following World War II, the allied powers sought to improve global financial stability and ensure that basic rights were codified and protected at the international level. The UN Charter and the Bretton Woods agreements ... -
Human stem cell delivery for treatment of large segmental bone defects
(Proceedings of the National Academy of Sciences, 2010-01-19)Local or systemic stem cell delivery has the potential to promote repair of a variety of damaged or degenerated tissues. Although various stem cell sources have been investigated for bone repair, few comparative reports ... -
Human stem cell modeling for amyotrophic lateral sclerosis
(NUI Galway, 2022-09-28)Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs). Most ALS cases are sporadic, with no family history or known genetic ...