Browsing by Title

Now showing items 5634-5653 of 14646

    • Functional studies on the role of notch signaling in hydractinia development 

      Gahan, James M.; Schnitzler, Christine E.; DuBuc, Timothy Q.; Doonan, Liam B.; Kanska, Justyna; Gornik, Sebastian G.; Barreira, Sofia; Thompson, Kerry; Schiffer, Philipp; Baxevanis, Andreas D.; Frank, Uri (Elsevier BV, 2017-08-01)
      The function of Notch signaling was previously studied in two cnidarians, Hydra and Nematostella, representing the lineages Hydrozoa and Anthozoa, respectively. Using pharmacological inhibition in Hydra and a combination ...

    • Functional variants at the 11q13 risk locus for breast cancer regulate cyclin d1 expression through long-range enhancers 

      French, Juliet D.; Ghoussaini, Maya; Edwards, Stacey L.; Meyer, Kerstin B.; Michailidou, Kyriaki; Ahmed, Shahana; Khan, Sofia; Maranian, Mel J.; O’Reilly, Martin; Hillman, Kristine M.; Betts, Joshua A.; Carroll, Thomas; Bailey, Peter J.; Dicks, Ed; Beesley, Jonathan; Tyrer, Jonathan; Maia, Ana-Teresa; Beck, Andrew; Knoblauch, Nicholas W.; Chen, Constance; Kraft, Peter; Barnes, Daniel; González-Neira, Anna; Alonso, M. Rosario; Herrero, Daniel; Tessier, Daniel C.; Vincent, Daniel; Bacot, Francois; Luccarini, Craig; Baynes, Caroline; Conroy, Don; Dennis, Joe; Bolla, Manjeet K.; Wang, Qin; Hopper, John L.; Southey, Melissa C.; Schmidt, Marjanka K.; Broeks, Annegien; Verhoef, Senno; Cornelissen, Sten; Muir, Kenneth; Lophatananon, Artitaya; Stewart-Brown, Sarah; Siriwanarangsan, Pornthep; Fasching, Peter A.; Loehberg, Christian R.; Ekici, Arif B.; Beckmann, Matthias W.; Peto, Julian; dos Santos Silva, Isabel; Johnson, Nichola; Aitken, Zoe; Sawyer, Elinor J.; Tomlinson, Ian; Kerin, Michael J.; Miller, Nicola; Marme, Frederik; Schneeweiss, Andreas; Sohn, Christof; Burwinkel, Barbara; Guénel, Pascal; Truong, Thérèse; Laurent-Puig, Pierre; Menegaux, Florence; Bojesen, Stig E.; Nordestgaard, Børge G.; Nielsen, Sune F.; Flyger, Henrik; Milne, Roger L.; Zamora, M. Pilar; Arias Perez, Jose Ignacio; Benitez, Javier; Anton-Culver, Hoda; Brenner, Hermann; Müller, Heiko; Arndt, Volker; Stegmaier, Christa; Meindl, Alfons; Lichtner, Peter; Schmutzler, Rita K.; Engel, Christoph; Brauch, Hiltrud; Hamann, Ute; Justenhoven, Christina; Aaltonen, Kirsimari; Heikkilä, Päivi; Aittomäki, Kristiina; Blomqvist, Carl; Matsuo, Keitaro; Ito, Hidemi; Iwata, Hiroji; Sueta, Aiko; Bogdanova, Natalia V.; Antonenkova, Natalia N.; Dörk, Thilo; Lindblom, Annika; Margolin, Sara; Mannermaa, Arto; Kataja, Vesa; Kosma, Veli-Matti; Hartikainen, Jaana M.; Wu, Anna H.; Tseng, Chiu-chen; Van Den Berg, David; Stram, Daniel O.; Lambrechts, Diether; Peeters, Stephanie; Smeets, Ann; Floris, Giuseppe; Chang-Claude, Jenny; Rudolph, Anja; Nickels, Stefan; Flesch-Janys, Dieter; Radice, Paolo; Peterlongo, Paolo; Bonanni, Bernardo; Sardella, Domenico; Couch, Fergus J.; Wang, Xianshu; Pankratz, Vernon S.; Lee, Adam; Giles, Graham G.; Severi, Gianluca; Baglietto, Laura; Haiman, Christopher A.; Henderson, Brian E.; Schumacher, Fredrick; Le Marchand, Loic; Simard, Jacques; Goldberg, Mark S.; Labrèche, France; Dumont, Martine; Teo, Soo Hwang; Yip, Cheng Har; Ng, Char-Hong; Vithana, Eranga Nishanthie; Kristensen, Vessela; Zheng, Wei; Deming-Halverson, Sandra; Shrubsole, Martha; Long, Jirong; Winqvist, Robert; Pylkäs, Katri; Jukkola-Vuorinen, Arja; Grip, Mervi; Andrulis, Irene L.; Knight, Julia A.; Glendon, Gord; Mulligan, Anna Marie; Devilee, Peter; Seynaeve, Caroline; García-Closas, Montserrat; Figueroa, Jonine; Chanock, Stephen J.; Lissowska, Jolanta; Czene, Kamila; Klevebring, Daniel; Schoof, Nils; Hooning, Maartje J.; Martens, John W.M.; Collée, J. Margriet; Tilanus-Linthorst, Madeleine; Hall, Per; Li, Jingmei; Liu, Jianjun; Humphreys, Keith; Shu, Xiao-Ou; Lu, Wei; Gao, Yu-Tang; Cai, Hui; Cox, Angela; Balasubramanian, Sabapathy P.; Blot, William; Signorello, Lisa B.; Cai, Qiuyin; Pharoah, Paul D.P.; Healey, Catherine S.; Shah, Mitul; Pooley, Karen A.; Kang, Daehee; Yoo, Keun-Young; Noh, Dong-Young; Hartman, Mikael; Miao, Hui; Sng, Jen-Hwei; Sim, Xueling; Jakubowska, Anna; Lubinski, Jan; Jaworska-Bieniek, Katarzyna; Durda, Katarzyna; Sangrajrang, Suleeporn; Gaborieau, Valerie; McKay, James; Toland, Amanda E.; Ambrosone, Christine B.; Yannoukakos, Drakoulis; Godwin, Andrew K.; Shen, Chen-Yang; Hsiung, Chia-Ni; Wu, Pei-Ei; Chen, Shou-Tung; Swerdlow, Anthony; Ashworth, Alan; Orr, Nick; Schoemaker, Minouk J.; Ponder, Bruce A.J.; Nevanlinna, Heli; Brown, Melissa A.; Chenevix-Trench, Georgia; Easton, Douglas F.; Dunning, Alison M. (Elsevier BV, 2013-04-01)
      Analysis of 4,405 variants in 89,050 European subjects from 41 case-control studies identified three independent association signals for estrogen-receptor-positive tumors at 11q13. The strongest signal maps to a transcriptional ...

    • Functional  -aminobutyrate shunt in listeria monocytogenes: role in acid tolerance and succinate biosynthesis 

      Feehily, C.; O'Byrne, C. P.; Karatzas, K. A. G. (American Society for Microbiology, 2012-10-12)
      Listeria monocytogenes, the causative agent of human listeriosis, is known for its ability to withstand severe environmental stresses. The glutamate decarboxylase (GAD) system is one of the principal systems utilized by ...

    • Functionality of ngf-protected pc12 cells following exposure to 6-hydroxydopamine 

      Kavanagh, Edel T.; Loughlin, John P.; Herbert, Kate Reed; Dockery, Peter; Samali, Afshin; Doyle, Karen M.; Gorman, Adrienne M. (Elsevier BV, 2006-12-01)

    • Functionalization and fragmentation during ambient organic aerosol aging: application of the 2-d volatility basis set to field studies 

      Murphy, B. N.; Donahue, N. M.; Fountoukis, C.; Dall'Osto, M.; O'Dowd, C.; Kiendler-Scharr, A.; Pandis, S. N. (Copernicus GmbH, 2012-11-16)
      Multigenerational oxidation chemistry of atmospheric organic compounds and its effects on aerosol loadings and chemical composition is investigated by implementing the Two-Dimensional Volatility Basis Set (2-D-VBS) in a ...

    • Functionalization of the living diatom thalassiosira weissflogii with thiol moieties 

      Lang, Yvonne; del Monte, Francisco; Collins, Liam; Rodriguez, Brian J.; Thompson, Kerry; Dockery, Peter; Finn, David P.; Pandit, Abhay (Springer Nature, 2013-11-01)
      Biomineralization processes identified within diatoms have inspired the design of synthetic silica structures in vitro using alkoxysilane precursors. Here we explore the use of the machinery within the living diatom to ...

    • Functionalized scaffold-mediated interleukin 10 gene delivery significantly improves survival rates of stem cells in vivo 

      Holladay, Carolyn; Power, Karen; Sefton, Michael; O'Brien, Timothy; Gallagher, William M.; Pandit, Abhay (Elsevier BV, 2011-05-01)
      While stem cell transplantation could potentially treat a variety of disorders, clinical studies have not yet demonstrated conclusive benefits. This may be partly because transplanted stem cells have low survival rates, ...

    • Fundamental Rights Protection in the European Union post Lisbon Treaty 

      Pech, Laurent; Groussot, Xavier (Fondation Robert Schuman, 2010-06-14)
      With the entry into force of the Lisbon Treaty last December, the EU Charter of Fundamental Rights has finally become a legally binding and core element of the Union's legal order. This is not, however, the sole major ...

    • A fundamental study on the pyrolysis of hydrocarbons 

      Nagaraja, Shashank S.; Sahu, Amrit B.; Panigrahy, Snehasish; Curran, Henry J. (Elsevier, 2021-07-10)
      A newly developed detailed chemical kinetic mechanism, NUIGMech1.1, is used to study the pyrolysis of C1 ¿ C7 hydrocarbons at a constant initial fuel concentration in the temperature range 900 ¿ 2000 K. We observe that, ...

    • Fundamentals of in situ digital camera methodology for water quality monitoring of coast and ocean 

      Goddijn-Murphy, Lonneke; Dailloux, Damien; White, Martin; Bowers, Dave (MDPI AG, 2009-07-22)
      Conventional digital cameras, the Nikon Coolpix885 (R) and the SeaLife ECOshot (R), were used as in situ optical instruments for water quality monitoring. Measured response spectra showed that these digital cameras are ...

    • The Funerary Bowls and Vases of the Irish Bronze Age 

      Ó Ríordáin, Breandán; Waddell, John (Galway University Press, 1993)
      This illustrated corpus of pottery from burial contexts in Bronze Age Ireland c. 2500-1500 BC was prepared by John Waddell with the assistance of Breandán Ó Ríordáin and the National Museum of Ireland. It includes a study ...

    • Fungal enzymes for bio-products from sustainable and waste biomass 

      Gupta, Vijai K.; Kubicek, Christian P.; Berrin, Jean-Guy; Wilson, David W.; Couturier, Marie; Berlin, Alex; Filho, Edivaldo X.F.; Ezeji, Thaddeus (Elsevier BV, 2016-07-01)
      Lignocellulose, the most abundant renewable carbon source on earth, is the logical candidate to replace fossil carbon as the major biofuel raw material. Nevertheless, the technologies needed to convert lignocellulose into ...

    • A further analysis of the role of heterogeneity in coevolutionary spatial games 

      Cardinot, Marcos; Griffith, Josephine; O'Riordan, Colm (Elsevier, 2017-11-04)
      Heterogeneity has been studied as one of the most common explanations of the puzzle of cooperation in social dilemmas. A large number of papers have been published discussing the effects of increasing heterogeneity in ...

    • Further insights into the catalytical properties of deglycosylated pyranose dehydrogenase fromagaricus meleagrisrecombinantly expressed inpichia pastoris 

      Yakovleva, Maria E.; Killyéni, Anikó; Seubert, Oliver; Ó Conghaile, Peter; MacAodha, Domhnall; Leech, Dónal; Gonaus, Christoph; Popescu, Ionel Catalin; Peterbauer, Clemens K.; Kjellström, Sven; Gorton, Lo (American Chemical Society (ACS), 2013-10-15)
      The present study focuses on fragmented deglycosylated pyranose dehydrogenase (fdgPDH) from Agaricus meleagris recombinantly expressed in Pichia pastoris. Fragmented deglycosylated PDH is formed from the deglycosylated ...

    • Further studies in self-directed learning in physics at the University of Limerick, Ireland 

      McCauley, Veronica; McClelland, George (International​​​ Society for Self-Directed Learning (ISSDL), 2004)
      This article reports on two SDL studies of undergraduate physics students and postgraduate science students at the University of Limerick, Ireland. Initial studies (McCauley and McClelland, 2001) indicated that the majority ...

    • A fusion of research-informed teaching and teaching-informed research: Designing a scalable online ecosystem for new partnerships in educational research 

      Connolly, Cornelia; Hall, Tony; Ryan, Marie; McMahon, Jennifer; McGann, Marek; Egan, Alison (Australasian Society for Computers in Learning in Tertiary Education, 2020-10-26)
      This paper examines the unbundling of research in the context of the Teachers Research Exchange (T-REX) platform, the national flagship Internet platform in Ireland for teachers to access, use and engage in research. This ...

    • Future challenges in cephalopod research 

      Xavier, José C.; Allcock, A. Louise; Cherel, Yves; Lipinski, Marek R.; Pierce, Graham J.; Rodhouse, Paul G.K.; Rosa, Rui; Shea, Elizabeth K.; Strugnell, Jan M.; Vidal, Erica A.G.; Villanueva, Roger; Ziegler, Alexander (Cambridge University Press (CUP), 2014-06-26)
      Cephalopods (Mollusca: Cephalopoda) play an important role as keystone invertebrates in various marine ecosystems, as well as being a valuable fisheries resource. At the World Malacological Congress, held 21 - 28 July 2013 ...

    • Future directions in managing aniridia-associated keratopathy 

      van Velthoven, Arianne J.H.; Utheim, Tor P.; Notara, Maria; Bremond-Gignac, Dominique; Figueiredo, Francisco C.; Skottman, Heli; Aberdam, Daniel; Daniels, Julie T.; Ferrari, Giulio; Grupcheva, Christina; Koppen, Carina; Parekh, Mohit; Ritter, Thomas; Romano, Vito; Ferrari, Stefano; Cursiefen, Claus; Lagali, Neil; LaPointe, Vanessa L.S.; Dickman, Mor M. (Elsevier, 2023-05-04)
      Congenital aniridia is a panocular disorder that is typically characterized by iris hypoplasia and aniridia-associated keratopathy (AAK). AAK results in the progressive loss of corneal transparency and thereby loss of ...

    • Future phosphorus: advancing new '2D' allotropes and growing a sustainable bio economy 

      Jarvie, Helen P.; Flaten, Don; Sharpley, Andrew N.; Kleinman, Peter J. A.; Healy, Mark G.; King, Stephen M. (Crop Science Society of America with American Society of Agronomy and Soil Science Society of America, 2019-07-11)
      With more than 40 countries currently proposing to boost their national bioeconomies, there is no better time for a clarion call for a new bioeconomy, which, at its core, tackles the current disparities and inequalities ...

    • Future research in agile systems development: applying open innovation principles within the agile organisation 

      Conboy, Kieran; Morgan, Lorraine (Springer Verlag, 2010)
      A particular strength of agile approaches is that they move away from 'introverted' development and intimately involve the customer in all areas of development, supposedly leading to the development of a more innovative ...