Now showing items 4781-4800 of 14646

    • Evidence that breast cancer risk at the 2q35 locus is mediated through igfbp5 regulation 

      Ghoussaini, Maya; Edwards, Stacey L.; Michailidou, Kyriaki; Nord, Silje; Cowper-Sal·lari, Richard; Desai, Kinjal; Kar, Siddhartha; Hillman, Kristine M.; Kaufmann, Susanne; Glubb, Dylan M.; Beesley, Jonathan; Dennis, Joe; Bolla, Manjeet K.; Wang, Qin; Dicks, Ed; Guo, Qi; Schmidt, Marjanka K.; Shah, Mitul; Luben, Robert; Brown, Judith; Czene, Kamila; Darabi, Hatef; Eriksson, Mikael; Klevebring, Daniel; Bojesen, Stig E.; Nordestgaard, Børge G.; Nielsen, Sune F.; Flyger, Henrik; Lambrechts, Diether; Thienpont, Bernard; Neven, Patrick; Wildiers, Hans; Broeks, Annegien; Van’t Veer, Laura J.; Th Rutgers, Emiel J.; Couch, Fergus J.; Olson, Janet E.; Hallberg, Emily; Vachon, Celine; Chang-Claude, Jenny; Rudolph, Anja; Seibold, Petra; Flesch-Janys, Dieter; Peto, Julian; dos-Santos-Silva, Isabel; Gibson, Lorna; Nevanlinna, Heli; Muranen, Taru A.; Aittomäki, Kristiina; Blomqvist, Carl; Hall, Per; Li, Jingmei; Liu, Jianjun; Humphreys, Keith; Kang, Daehee; Choi, Ji-Yeob; Park, Sue K.; Noh, Dong-Young; Matsuo, Keitaro; Ito, Hidemi; Iwata, Hiroji; Yatabe, Yasushi; Guénel, Pascal; Truong, Thérèse; Menegaux, Florence; Sanchez, Marie; Burwinkel, Barbara; Marme, Frederik; Schneeweiss, Andreas; Sohn, Christof; Wu, Anna H.; Tseng, Chiu-chen; Van Den Berg, David; Stram, Daniel O.; Benitez, Javier; Zamora, M. Pilar; Perez, Jose Ignacio Arias; Menéndez, Primitiva; Shu, Xiao-Ou; Lu, Wei; Gao, Yu-Tang; Cai, Qiuyin; Cox, Angela; Cross, Simon S.; Reed, Malcolm W. R.; Andrulis, Irene L.; Knight, Julia A.; Glendon, Gord; Tchatchou, Sandrine; Sawyer, Elinor J.; Tomlinson, Ian; Kerin, Michael J.; Miller, Nicola; Haiman, Christopher A.; Henderson, Brian E.; Schumacher, Fredrick; Le Marchand, Loic; Lindblom, Annika; Margolin, Sara; TEO, Soo Hwang; YIP, Cheng Har; Lee, Daphne S. C.; Wong, Tien Y.; Hooning, Maartje J.; Martens, John W. M.; Collée, J. Margriet; van Deurzen, Carolien H. M.; Hopper, John L.; Southey, Melissa C.; Tsimiklis, Helen; Kapuscinski, Miroslav K.; Shen, Chen-Yang; Wu, Pei-Ei; Yu, Jyh-Cherng; Chen, Shou-Tung; Alnæs, Grethe Grenaker; Borresen-Dale, Anne-Lise; Giles, Graham G.; Milne, Roger L.; McLean, Catriona; Muir, Kenneth; Lophatananon, Artitaya; Stewart-Brown, Sarah; Siriwanarangsan, Pornthep; Hartman, Mikael; Miao, Hui; Buhari, Shaik Ahmad Bin Syed; Teo, Yik Ying; Fasching, Peter A.; Haeberle, Lothar; Ekici, Arif B.; Beckmann, Matthias W.; Brenner, Hermann; Dieffenbach, Aida Karina; Arndt, Volker; Stegmaier, Christa; Swerdlow, Anthony; Ashworth, Alan; Orr, Nick; Schoemaker, Minouk J.; García-Closas, Montserrat; Figueroa, Jonine; Chanock, Stephen J.; Lissowska, Jolanta; Simard, Jacques; Goldberg, Mark S.; Labrèche, France; Dumont, Martine; Winqvist, Robert; Pylkäs, Katri; Jukkola-Vuorinen, Arja; Brauch, Hiltrud; Brüning, Thomas; Koto, Yon-Dschun; Radice, Paolo; Peterlongo, Paolo; Bonanni, Bernardo; Volorio, Sara; Dörk, Thilo; Bogdanova, Natalia V.; Helbig, Sonja; Mannermaa, Arto; Kataja, Vesa; Kosma, Veli-Matti; Hartikainen, Jaana M.; Devilee, Peter; Tollenaar, Robert A. E. M.; Seynaeve, Caroline; Van Asperen, Christi J.; Jakubowska, Anna; Lubinski, Jan; Jaworska-Bieniek, Katarzyna; Durda, Katarzyna; Slager, Susan; Toland, Amanda E.; Ambrosone, Christine B.; Yannoukakos, Drakoulis; Sangrajrang, Suleeporn; Gaborieau, Valerie; Brennan, Paul; McKay, James; Hamann, Ute; Torres, Diana; Zheng, Wei; Long, Jirong; Anton-Culver, Hoda; Neuhausen, Susan L.; Luccarini, Craig; Baynes, Caroline; Ahmed, Shahana; Maranian, Mel; Healey, Catherine S.; González-Neira, Anna; Pita, Guillermo; Alonso, M. Rosario; Álvarez, Nuria; Herrero, Daniel; Tessier, Daniel C.; Vincent, Daniel; Bacot, Francois; de Santiago, Ines; Carroll, Jason; Caldas, Carlos; Brown, Melissa A.; Lupien, Mathieu; Kristensen, Vessela N.; Pharoah, Paul D P; Chenevix-Trench, Georgia; French, Juliet D; Easton, Douglas F.; Dunning, Alison M.; Chenevix-Trench, Georgia; Webb, Penny; Bowtell, David; De Fazio, Anna (Springer Nature, 2014-09-23)
      GWAS have identified a breast cancer susceptibility locus on 2q35. Here we report the fine mapping of this locus using data from 101,943 subjects from 50 case-control studies. We genotype 276 SNPs using the 'iCOGS' genotyping ...
    • Evidence-based training of health professionals to inform families about disability 

      Harnett, Alison; Bettendorf, Erin; Tierney, Edel; Guerin, Suzanne; O'Rourke, Margaret; Hourihane, Jonathan (BMJ Publishing Group, 2013-05-09)
      Objective The development, delivery and evaluation of a training programme for medical and nursing professionals on best practice for informing families of their child’s disability. Design A 2 h training course on ‘Best ...
    • Evolution and diversity of plant cell walls: from algae to flowering plants 

      Popper, Zoë A.; Gurvan, Michel; Hervé, Cécile; Domozych, David S.; Willats, William G.T.; Tuohy, Maria G.; Kloareg, Bernard; Stengel, Dagmar B. (Annual Reviews, 2011-02-22)
      All photosynthetic multicellular Eukaryotes, including land plants and algae, have cells that are surrounded by a dynamic, complex, carbohydrate-rich cell wall. The cell wall exerts considerable biological and biomechanical ...
    • The evolution and future of lean Six Sigma 4.0 

      Antony, Jiju; McDermott, Olivia; Powell, Daryl; Sony, Michael (Emerald, 2022-05-24)
      Purpose This purpose of this study is to provide an overview of the current state of research on Lean Six Sigma (LSS) and Industry 4.0 and the key aspects of the relationships between them. The research analyses LSS's ...
    • Evolution equations with causal operators 

      Agarwal, Ravi P.; Arshad, Sadia; Lupulescu, Vasile; 'Regan, Donal (Element d.o.o., 2015-01-01)
      In this paper we present an existence result for causal functional evolution equations. The result is obtained under a condition with respect to the Hausdorff measure of noncompactness. An application with partial differential ...
    • The Evolution of a Kernel-Based Distance Metric for k-NN Regression 

      Madden, Michael G.; Howley, Tom (2007)
      k-Nearest Neighbours (k-NN) is a well understood and widely-used approach to classification and regression problems. In many cases, such applications of k-NN employ the standard Euclidean distance metric for the determination ...
    • Evolution of a research field—a micro (rna) example 

      Casey, Máire-Caitlín; Kerin, Michael J.; Brown, James A.; Sweeney, Karl J. (PeerJ, 2015-03-17)
      Background. Every new scientific field can be traced back to a single, seminal publication. Therefore, a bibliometric analysis can yield significant insights into the history and potential future of a research field. This ...
    • Evolution of anisotropy in soft tissue 

      Murphy, J. G. (The Royal Society, 2013-11-20)
      The phenomenological approach to the modelling of the mechanical response of arteries usually assumes a reduced form of the strain-energy function in order to reduce the mathematical complexity of the model. A common ...
    • Evolution of astacin-like metalloproteases in animals and their function in development 

      Mohrlen, Frank; Maniura, Melanie; Plickert, Gunter; Frohme, Marcus; Frank, Uri (Wiley-Blackwell, 2006-03-01)
      Astacin-like metalloproteases are ubiquitous in the animal kingdom but their phylogenetic relationships and ancient functions within the Metazoa are unclear. We have cloned and characterized four astacin-like cDNAs from ...
    • The evolution of behaviours in swarms of robots 

      Holland, Jane (NUI Galway, 2019-12-09)
      Evolutionary swarm robotics uses evolutionary computational techniques to synthesise behaviours for a group of autonomous robots. In a swarm of robots, the collective behaviour of the robots results from the local interactions ...
    • Evolution of breast cancer management in ireland: a decade of change 

      Heneghan, Helen M; Prichard, Ruth S; Devaney, Amanda; Sweeney, Karl J; Malone, C; McLaughlin, Ray; Kerin, Michael J (Springer Nature, 2009-09-18)
      Background: Over the last decade there has been a paradigm shift in the management of breast cancer, subsequent to revised surgical oncology guidelines and consensus statements which were derived in light of landmark breast ...
    • Evolution of cooperation in N-player social dilemmas: The importance of being mobile 

      Gibbons, Maud D.; O'Riordan, Colm; Griffith, Josephine (SciTePress Digital Library, 2016)
      This paper addresses issues regarding the emergence of cooperation in evolutionary, spatial game-theoretic simulations. In the model considered, agents participate in a social dilemma with their neighbours and have the ...
    • Evolution of Groups for Common Pool Resource Sharing 

      Cunningham, Alan (2013-09-27)
      This thesis concerns the creation of groups of characters which, through the use simple actions, cooperate and coordinate to survive together. These groups are created automatically using Evolutionary Computation methods. A ...
    • The evolution of Ireland’s medical device cluster and its future direction 

      McKernan, David; McDermott, Olivia (MDPI, 2022-08-16)
      Ireland has developed a highly successful medical device cluster. Most of the industry started from USA multinationals that moved to Ireland in the 1990s. An ecosystem has now developed with strong linkages between ...
    • Evolution of sensory development – lessons from the lateral line 

      Schlosser, Gerhard (S. Karger AG, 2012-01-01)
    • Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes 

      Hockman, Dorit; Burns, Alan J; Schlosser, Gerhard; Gates, Keith P; Jevans, Benjamin; Mongera, Alessandro; Fisher, Shannon; Unlu, Gokhan; Knapik, Ela W; Kaufman, Charles K; Mosimann, Christian; Zon, Leonard I; Lancman, Joseph J; Dong, P Duc S; Lickert, Heiko; Tucker, Abigail S; Baker, Clare V H (eLife Sciences Organisation, Ltd., 2017-04-07)
      The evolutionary origins of the hypoxia-sensitive cells that trigger amniote respiratory reflexes carotid body glomus cells, and 'pulmonary neuroendocrine cells' (PNECs) - are obscure. Homology has been proposed between ...
    • Evolution of the inflammatory and fibroproliferative responses during resolution and repair after ventilator-induced lung injury in the rat 

      Curley, Gerard F.; Contreras, Maya; Higgins, Brendan; OʼKane, Cecilia; McAuley, Daniel F.; OʼToole, Daniel; Laffey, John G. (Ovid Technologies (Wolters Kluwer Health), 2011-11-01)
      Background: The time course and mechanisms of resolution and repair, and the potential for fibrosis following ventilation-induced lung injury (VILI), are unclear. We sought to examine the pattern of inflammation, injury, ...
    • An evolutionary approach to automatic kernel construction 

      Madden, Michael G.; Howley, Tom (2006)
      Abstract. Kernel-based learning presents a unified approach to machine learning problems such as classification and regression. The selection of a kernel and associated parameters is a critical step in the application of ...
    • An evolutionary approach to formation control with mobile robots 

      Holland, Jane; Griffith, Josephine; O'Riordan, Colm (SciTePress Digital Library, 2016)
      The field of swarm robotics studies multi-robot systems, emphasising decentralised and self-organising behaviours that deal with limited individual abilities, local sensing and local communication. A robotic system needs ...
    • Evolutionary developmental biology: towards a spineless stickleback 

      Arthur, W (Springer Nature, 2004-09-01)