Browsing University of Galway Support Services by Subject "kala-azar"
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Evolutionary genomics of epidemic visceral leishmaniasis in the indian subcontinent
(eLife Sciences Organisation, Ltd., 2016-03-22)Leishmania donovani causes visceral leishmaniasis (VL), the second most deadly vector borne parasitic disease. A recent epidemic in the Indian subcontinent (ISC) caused up to 80% of global VL and over 30,000 deaths per ... -
in vitro selection of miltefosine resistance in promastigotes of leishmania donovani from nepal: genomic and metabolomic characterization
(Wiley-Blackwell, 2016-02-09)In this study, we followed the genomic, lipidomic and metabolomic changes associated with the selection of miltefosine (MIL) resistance in two clinically derived Leishmania donovani strains with different inherent resistance ...