Browsing University of Galway Support Services by Author "Tajber, Lidia"
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Amorphous solid dispersions of sulfonamide/soluplus® and sulfonamide/pvp prepared by ball milling
Caron, Vincent; Hu, Yun; Tajber, Lidia; Erxleben, Andrea; Corrigan, Owen I.; McArdle, Patrick; Healy, Anne Marie (American Association of Pharmaceutical Scientists (AAPS), 2013-02-07)The aim of this paper is to investigate the physicochemical properties of binary amorphous dispersions of poorly soluble sulfonamide/polymeric excipient prepared by ball milling. The sulfonamides selected were sulfathiazole ... -
Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling
Curtin, Vincent; Amharar, Youness; Hu, Yun; Erxleben, Andrea; McArdle, Patrick; Caron, Vincent; Tajber, Lidia; Corrigan, Owen I.; Healy, Anne Marie (American Chemical Society (ACS), 2013-01-07)The coprocessing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (T-g) is a recognized strategy to stabilize the amorphous form of a drug. This work investigates ... -
Modification of the solid-state nature of sulfathiazole and sulfathiazole sodium by spray drying
Bianco, Stefano; Caron, Vincent; Tajber, Lidia; Corrigan, Owen I.; Nolan, Lorraine; Hu, Yun; Healy, Anne Marie (American Association of Pharmaceutical Scientists (AAPS), 2012-05-02)Solid-state characterisation of a drug following pharmaceutical processing and upon storage is fundamental to successful dosage form development. The aim of the study was to investigate the effects of using different ...