Browsing University of Galway Support Services by Author "Kadimisetty, Karteek"
Now showing items 1-8 of 8
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3d-printed bioanalytical devices
Bishop, Gregory W; Satterwhite-Warden, Jennifer E; Kadimisetty, Karteek; Rusling, James F (IOP Publishing, 2016-06-02)While 3D printing technologies first appeared in the 1980s, prohibitive costs, limited materials, and the relatively small number of commercially available printers confined applications mainly to prototyping for manufacturing ... -
3d-printed fluidic devices for nanoparticle preparation and flow-injection amperometry using integrated prussian blue nanoparticle-modified electrodes
Bishop, Gregory W.; Satterwhite, Jennifer E.; Bhakta, Snehasis; Kadimisetty, Karteek; Gillette, Kelsey M.; Chen, Eric; Rusling, James F. (American Chemical Society (ACS), 2015-05-19)A consumer-grade fused filament fabrication (PP) 31) printer was used to construct fluidic devices for nanoparticle preparation and electrochemical sensing. Devices were printed using poly(ethylene terephthalate) and ... -
3d-printed supercapacitor-powered electrochemiluminescent protein immunoarray
Kadimisetty, Karteek; Mosa, Islam M.; Malla, Spundana; Satterwhite-Warden, Jennifer E.; Kuhns, Tyler M.; Faria, Ronaldo C.; Lee, Norman H.; Rusling, James F. (Elsevier BV, 2016-03-01) -
Automated multiplexed ecl immunoarrays for cancer biomarker proteins
Kadimisetty, Karteek; Malla, Spundana; Sardesai, Naimish P.; Joshi, Amit A.; Faria, Ronaldo C.; Lee, Norman H.; Rusling, James F. (American Chemical Society (ACS), 2015-04-21)Point-of-care diagnostics based on multiplexed protein measurements face challenges of simple, automated, low-cost, and high-throughput operation-with high sensitivity. Herein, we describe an automated, microprocessor-controlled ... -
Chemical selectivity of nucleobase adduction relative to in vivo mutation sites on exon 7 fragment of p53 tumor suppressor gene
Malla, Spundana; Kadimisetty, Karteek; Fu, You-Jun; Choudhary, Dharamainder; Jansson, Ingela; Schenkman, John B.; Rusling, James F. (Royal Society of Chemistry (RSC), 2015-01-01)Damage to p53tumor suppressor gene is found in half of all human cancers. Databases integrating studies of large numbers of tumors and cancer cell cultures show that mutation sites of specific p53 codons are correlated ... -
Electrochemistry-based approaches to low cost, high sensitivity, automated, multiplexed protein immunoassays for cancer diagnostics
Dixit, Chandra K.; Kadimisetty, Karteek; Otieno, Brunah A.; Tang, Chi; Malla, Spundana; Krause, Colleen E.; Rusling, James F. (Royal Society of Chemistry (RSC), 2016-01-01)Early detection and reliable diagnostics are keys to effectively design cancer therapies with better prognoses. The simultaneous detection of panels of biomarker proteins holds great promise as a general tool for reliable ... -
Methyl-cytosine-driven structural changes enhance adduction kinetics of an exon 7 fragment of the p53 gene
Malla, Spundana; Kadimisetty, Karteek; Fu, You-Jun; Choudhary, Dharamainder; Schenkman, John B.; Rusling, James F. (Springer Nature, 2017-01-19)Methylation of cytosine (C) at C-phosphate-guanine (CpG) sites enhances reactivity of DNA towards electrophiles. Mutations at CpG sites on the p53 tumor suppressor gene that can result from these adductions are in turn ... -
Paper-based electrochemiluminescent screening for genotoxic activity in the environment
Mani, Vigneshwaran; Kadimisetty, Karteek; Malla, Spundana; Joshi, Amit A.; Rusling, James F. (American Chemical Society (ACS), 2013-02-19)A low cost, microfluidic paper electrochemical device (mu PED) was fabricated using screen printing of electrodes and heat transfer of patterned wax paper onto filter paper. The mu PED features films of a light-emitting ...