Now showing items 1-14 of 14

    • Brain structural effects of psychopharmacological treatment in bipolar disorder 

      McDonald, Colm (Bentham Science Publishers Ltd., 2015-08-31)
      Bipolar disorder is associated with subtle neuroanatomical deficits including lateral ventricular enlargement, grey matter deficits incorporating limbic system structures, and distributed white matter pathophysiology. ...
    • Dementia in down’s syndrome: an mri comparison with alzheimer’s disease in the general population 

      Mullins, Diane; Daly, Eileen; Simmons, Andrew; Beacher, Felix; Foy, Catherine ML; Lovestone, Simon; Hallahan, Brian; Murphy, Kieran C; Murphy, Declan G (Springer Nature, 2013-01-01)
      Background: Down's syndrome (DS) is the most common genetic cause of intellectual disability. People with DS are at an increased risk of Alzheimer's disease (AD) compared to the general population. Neuroimaging studies of ...
    • Distribution of tract deficits in schizophrenia 

      Ellison-Wright, Ian; Nathan, Pradeep J; Bullmore, Edward T; Zaman, Rashid; Dudas, Robert B; Agius, Mark; Fernandez-Egea, Emilio; Müller, Ulrich; Dodds, Chris M; Forde, Natalie J; Scanlon, Cathy; Leemans, Alexander; McDonald, Colm; Cannon, Dara M. (Springer Nature, 2014-04-02)
      Background: Gray and white matter brain changes have been found in schizophrenia but the anatomical organizing process underlying these changes remains unknown. We aimed to identify gray and white matter volumetric changes ...
    • Effects of a novel schizophrenia risk variant rs7914558 at cnnm2 on brain structure and attributional style 

      Rose, E. J.; Hargreaves, A.; Morris, D.; Fahey, C.; Tropea, D.; Cummings, E.; Caltagirone, C.; Bossu, P.; Chiapponi, C.; Piras, F.; Spalletta, G.; Gill, M.; Corvin, A.; Donohoe, G. (Royal College of Psychiatrists, 2013-12-05)
      Background A single nucleotide polymorphism (rs7914558) within the cyclin M2 (CNNM2) gene was recently identified as a common risk variant for schizophrenia. The mechanism by which CNNM2 confers risk is unknown. Aims To ...
    • Meta-analysis of regional white matter volume in bipolar disorder with replication in an independent sample using coordinates, t-maps, and individual mri data 

      Pezzoli, Stefania; Emsell, Louise; Yip, Sarah W.; Dima, Danai; Giannakopoulos, Panteleimon; Zarei, Mojtaba; Tognin, Stefania; Arnone, Danilo; James, Anthony; Haller, Sven; Frangou, Sophia; Goodwin, Guy M.; McDonald, Colm; Kempton, Matthew J. (Elsevier BV, 2017-11-01)
      Converging evidence suggests that bipolar disorder (BD) is associated with white matter (WM) abnormalities. Meta-analyses of voxel based morphometry (VBM) data is commonly performed using published coordinates, however ...
    • Neurobiological trait abnormalities in bipolar disorder 

      Langan, C; McDonald, C (Springer Nature, 2009-05-19)
      Dissecting trait neurobiological abnormalities in bipolar disorder ( BD) from those characterizing episodes of mood disturbance will help elucidate the aetiopathogenesis of the illness. This selective review highlights the ...
    • Prefrontal cortical abnormalities in currently depressed versus currently remitted patients with major depressive disorder 

      Salvadore, Giacomo; Nugent, Allison C.; Lemaitre, Herve; Luckenbaugh, David A.; Tinsley, Ruth; Cannon, Dara M.; Neumeister, Alexander; Zarate, Carlos A.; Drevets, Wayne C. (Elsevier BV, 2011-02-01)
      Previous neuromorphometric investigations of major depressive disorder (MDD) have reported abnormalities in gray matter in several regions, although the results have been inconsistent across studies. Some discrepancies in ...
    • Prefrontal cortical thinning links to negative symptoms in schizophrenia via the enigma consortium 

      Walton, E.; Hibar, D. P.; van Erp, T. G. M.; Potkin, S. G.; Roiz-Santiañez, R.; Crespo-Facorro, B.; Suarez-Pinilla, P.; van Haren, N. E. M.; de Zwarte, S. M. C.; Kahn, R. S.; Cahn, W.; Doan, N. T.; Jørgensen, K. N.; Gurholt, T. P.; Agartz, I.; Andreassen, O. A.; Westlye, L. T.; Melle, I.; Berg, A. O.; Morch-Johnsen, L.; Færden, A.; Flyckt, L.; Fatouros-Bergman, H.; Jönsson, E. G.; Hashimoto, R.; Yamamori, H.; Fukunaga, M.; Jahanshad, N.; De Rossi, P.; Piras, F.; Banaj, N.; Spalletta, G.; Gur, R. E.; Gur, R. C.; Wolf, D. H.; Satterthwaite, T. D.; Beard, L. M.; Sommer, I. E.; Koops, S.; Gruber, O.; Richter, A.; Krämer, B.; Kelly, S.; Donohoe, G.; McDonald, C.; Cannon, D. M.; Corvin, A.; Gill, M.; Di Giorgio, A.; Bertolino, A.; Lawrie, S.; Nickson, T.; Whalley, H. C.; Neilson, E.; Calhoun, V. D.; Thompson, P. M.; Turner, J. A.; Ehrlich, S.; , (Cambridge University Press (CUP), 2017-05-26)
      Background. Our understanding of the complex relationship between schizophrenia symptomatology and etiological factors can be improved by studying brain-based correlates of schizophrenia. Research showed that impairments ...
    • Reduced occipital and prefrontal brain volumes in dysbindin-associated schizophrenia 

      Donohoe, Gary; Frodl, Thomas; Morris, Derek; Spoletini, Ilaria; Cannon, Dara M.; Cherubini, Andrea; Caltagirone, Carlo; Bossù, Paola; McDonald, Colm; Gill, Michael; Corvin, Aiden P; Spalletta, Gianfranco (Springer Nature, 2009-09-30)
      A three-marker C-A-T dysbindin haplotype identified by Williams et al (PMID: 15066891) is associated with increased risk for schizophrenia, decreased mRNA expression, poorer cognitive performance, and early sensory processing ...
    • Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the enigma consortium 

      van Erp, T G M; Hibar, D P; Rasmussen, J M; Glahn, D C; Pearlson, G D; Andreassen, O A; Agartz, I; Westlye, L T; Haukvik, U K; Dale, A M; Melle, I; Hartberg, C B; Gruber, O; Kraemer, B; Zilles, D; Donohoe, G; Kelly, S; McDonald, C; Morris, Derek W.; Cannon, D M; Corvin, A; Machielsen, M W J; Koenders, L; de Haan, L; Veltman, D J; Satterthwaite, T D; Wolf, D H; Gur, R C; Gur, R E; Potkin, S G; Mathalon, D H; Mueller, B A; Preda, A; Macciardi, F; Ehrlich, S; Walton, E; Hass, J; Calhoun, V D; Bockholt, H J; Sponheim, S R; Shoemaker, J M; van Haren, N E M; Pol, H E H; Ophoff, R A; Kahn, R S; Roiz-Santiañez, R; Crespo-Facorro, B; Wang, L; Alpert, K I; Jönsson, E G; Dimitrova, R; Bois, C; Whalley, H C; McIntosh, A M; Lawrie, S M; Hashimoto, R; Thompson, P M; Turner, J A (Springer Nature, 2015-06-02)
      The profile of brain structural abnormalities in schizophrenia is still not fully understood, despite decades of research using brain scans. To validate a prospective meta-analysis approach to analyzing multicenter ...
    • The arcuate fasciculus network and verbal deficits in psychosis 

      Kenney, Joanne P.M.; McPhilemy, Genevieve; Scanlon, Cathy; Najt, Pablo; McInerney, Shane; Arndt, Sophia; Scherz, Elisabeth; Byrne, Fintan; Leemans, Alexander; Jeurissen, Ben; Hallahan, Brian; McDonald, Colm; Cannon, Dara M. (Walter de Gruyter GmbH, 2017-11-02)
      Background: Verbal learning (VL) and fluency (VF) are prominent cognitive deficits in psychosis, of which the precise neuroanatomical contributions are not fully understood. We investigated the arcuate fasciculus (AF) and ...
    • The association of white matter volume in psychotic disorders with genotypic variation in nrg1, mog and cnp: a voxel-based analysis in affected individuals and their unaffected relatives 

      Cannon, D M; Walshe, M; Dempster, E; Collier, D A; Marshall, N; Bramon, E; Murray, R M; McDonald, C (Springer Nature, 2012-10-01)
      We investigated the role of variation in putative psychosis genes coding for elements of the white matter system by examining the contribution of genotypic variation in three single-nucleotide polymorphisms (SNPs) neuregulin ...
    • The enigma consortium: large-scale collaborative analyses of neuroimaging and genetic data 

      Thompson, Paul M.; ,; Stein, Jason L.; Medland, Sarah E.; Hibar, Derrek P.; Vasquez, Alejandro Arias; Renteria, Miguel E.; Toro, Roberto; Jahanshad, Neda; Schumann, Gunter; Franke, Barbara; Wright, Margaret J.; Martin, Nicholas G.; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy C.; Andreassen, Ole A.; Apostolova, Liana G.; Appel, Katja; Armstrong, Nicola J.; Aribisala, Benjamin; Bastin, Mark E.; Bauer, Michael; Bearden, Carrie E.; Bergmann, Ørjan; Binder, Elisabeth B.; Blangero, John; Bockholt, Henry J.; Bøen, Erlend; Bois, Catherine; Boomsma, Dorret I.; Booth, Tom; Bowman, Ian J.; Bralten, Janita; Brouwer, Rachel M.; Brunner, Han G.; Brohawn, David G.; Buckner, Randy L.; Buitelaar, Jan; Bulayeva, Kazima; Bustillo, Juan R.; Calhoun, Vince D.; Cannon, Dara M.; Cantor, Rita M.; Carless, Melanie A.; Caseras, Xavier; Cavalleri, Gianpiero L.; Chakravarty, M. Mallar; Chang, Kiki D.; Ching, Christopher R. K.; Christoforou, Andrea; Cichon, Sven; Clark, Vincent P.; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne E.; Czisch, Michael; Deary, Ian J.; de Geus, Eco J. C.; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; de Haan, Lieuwe; de Zubicaray, Greig I.; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas D.; Ehrlich, Stefan; Ekman, Carl Johan; Elvsåshagen, Torbjørn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernández, Guillén; Fisher, Simon E.; Foroud, Tatiana; Fox, Peter T.; Francks, Clyde; Frangou, Sophia; Frey, Eva Maria; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David C.; Godlewska, Beata; Goldstein, Rita Z.; Gollub, Randy L.; Grabe, Hans J.; Grimm, Oliver; Gruber, Oliver; Guadalupe, Tulio; Gur, Raquel E.; Gur, Ruben C.; Göring, Harald H. H.; Hagenaars, Saskia; Hajek, Tomas; Hall, Geoffrey B.; Hall, Jeremy; Hardy, John; Hartman, Catharina A.; Hass, Johanna; Hatton, Sean N.; Haukvik, Unn K.; Hegenscheid, Katrin; Heinz, Andreas; Hickie, Ian B.; Ho, Beng-Choon; Hoehn, David; Hoekstra, Pieter J.; Hollinshead, Marisa; Holmes, Avram J.; Homuth, Georg; Hoogman, Martine; Hong, L. Elliot; Hosten, Norbert; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Hwang, Kristy S.; Jack, Clifford R.; Jenkinson, Mark; Johnston, Caroline; Jönsson, Erik G.; Kahn, René S.; Kasperaviciute, Dalia; Kelly, Sinead; Kim, Sungeun; Kochunov, Peter; Koenders, Laura; Krämer, Bernd; Kwok, John B. J.; Lagopoulos, Jim; Laje, Gonzalo; Landen, Mikael; Landman, Bennett A.; Lauriello, John; Lawrie, Stephen M.; Lee, Phil H.; Le Hellard, Stephanie; Lemaître, Herve; Leonardo, Cassandra D.; Li, Chiang-shan; Liberg, Benny; Liewald, David C.; Liu, Xinmin; Lopez, Lorna M.; Loth, Eva; Lourdusamy, Anbarasu; Luciano, Michelle; Macciardi, Fabio; Machielsen, Marise W. J.; MacQueen, Glenda M.; Malt, Ulrik F.; Mandl, René; Manoach, Dara S.; Martinot, Jean-Luc; Matarin, Mar; Mather, Karen A.; Mattheisen, Manuel; Mattingsdal, Morten; Meyer-Lindenberg, Andreas; McDonald, Colm; McIntosh, Andrew M.; McMahon, Francis J.; McMahon, Katie L.; Meisenzahl, Eva; Melle, Ingrid; Milaneschi, Yuri; Mohnke, Sebastian; Montgomery, Grant W.; Morris, Derek W.; Moses, Eric K.; Mueller, Bryon A.; Muñoz Maniega, Susana; Mühleisen, Thomas W.; Müller-Myhsok, Bertram; Mwangi, Benson; Nauck, Matthias; Nho, Kwangsik; Nichols, Thomas E.; Nilsson, Lars-Göran; Nugent, Allison C.; Nyberg, Lars; Olvera, Rene L.; Oosterlaan, Jaap; Ophoff, Roel A.; Pandolfo, Massimo; Papalampropoulou-Tsiridou, Melina; Papmeyer, Martina; Paus, Tomas; Pausova, Zdenka; Pearlson, Godfrey D.; Penninx, Brenda W.; Peterson, Charles P.; Pfennig, Andrea; Phillips, Mary; Pike, G. Bruce; Poline, Jean-Baptiste; Potkin, Steven G.; Pütz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rietschel, Marcella; Rijpkema, Mark; Risacher, Shannon L.; Roffman, Joshua L.; Roiz-Santiañez, Roberto; Romanczuk-Seiferth, Nina; Rose, Emma J.; Royle, Natalie A.; Rujescu, Dan; Ryten, Mina; Sachdev, Perminder S.; Salami, Alireza; Satterthwaite, Theodore D.; Savitz, Jonathan; Saykin, Andrew J.; Scanlon, Cathy; Schmaal, Lianne; Schnack, Hugo G.; Schork, Andrew J.; Schulz, S. Charles; Schür, Remmelt; Seidman, Larry; Shen, Li; Shoemaker, Jody M.; Simmons, Andrew; Sisodiya, Sanjay M.; Smith, Colin; Smoller, Jordan W.; Soares, Jair C.; Sponheim, Scott R.; Sprooten, Emma; Starr, John M.; Steen, Vidar M.; Strakowski, Stephen; Strike, Lachlan; Sussmann, Jessika; Sämann, Philipp G.; Teumer, Alexander; Toga, Arthur W.; Tordesillas-Gutierrez, Diana; Trabzuni, Daniah; Trost, Sarah; Turner, Jessica; Van den Heuvel, Martijn; van der Wee, Nic J.; van Eijk, Kristel; van Erp, Theo G. M.; van Haren, Neeltje E. M.; van ‘t Ent, Dennis; van Tol, Marie-Jose; Valdés Hernández, Maria C.; Veltman, Dick J.; Versace, Amelia; Völzke, Henry; Walker, Robert; Walter, Henrik; Wang, Lei; Wardlaw, Joanna M.; Weale, Michael E.; Weiner, Michael W.; Wen, Wei; Westlye, Lars T.; Whalley, Heather C.; Whelan, Christopher D.; White, Tonya; Winkler, Anderson M.; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Zilles, David; Zwiers, Marcel P.; Thalamuthu, Anbupalam; Schofield, Peter R.; Freimer, Nelson B.; Lawrence, Natalia S.; Drevets, Wayne (Springer Nature, 2014-01-08)
      The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. ...
    • The mir-137 schizophrenia susceptibility variant rs1625579 does not predict variability in brain volume in a sample of schizophrenic patients and healthy individuals 

      Rose, Emma J.; Morris, Derek W.; Fahey, Ciara; Cannon, Dara; McDonald, Colm; Scanlon, Cathy; Kelly, Sinead; Gill, Michael; Corvin, Aiden; Donohoe, Gary (Wiley-Blackwell, 2014-07-05)