Browsing University of Galway Support Services by Subject "virulence"
Now showing items 1-19 of 19
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A deep-rough mutant of campylobacter jejuni 81-176 is noninvasive for intestinal epithelial cells
(American Society for Microbiology, 2004-03-23)A waaF mutant of Campylobacter jejuni 81-176 showed decreased invasion of INT407 cells in vitro and increased sensitivity to some antibiotics compared to what was seen with the wild-type strain. -
An essential role for coagulase instaphylococcus aureusbiofilm development reveals new therapeutic possibilities for device-related infections
(Oxford University Press (OUP), 2015-06-04)High-level resistance to antimicrobial drugs is a major factor in the pathogenesis of chronic Staphylococcus aureus biofilm-associated, medical device-related infections. Antimicrobial susceptibility analysis revealed that ... -
Characterization of the intracellular glutamate decarboxylase system: analysis of its function, transcription, and role in the acid resistance of various strains of listeria monocytogenes
(American Society for Microbiology, 2012-03-09)The glutamate decarboxylase (GAD) system is important for the acid resistance of Listeria monocytogenes. We previously showed that under acidic conditions, glutamate (Glt)/gamma-aminobutyrate (GABA) antiport is impaired ... -
Comparison of three serological methods for detection of lewis antigens on the surface of helicobacter pylori
(Oxford University Press (OUP), 2000-09-01) -
Effects of growth phase and temperature onσbactivity within alisteria monocytogenespopulation: evidence for rsbv-independent activation ofσbat refrigeration temperatures
(Hindawi Limited, 2014-01-01)The alternative sigma factor sigma(B) of Listeria monocytogenes is responsible for regulating the transcription of many of the genes necessary for adaptation to both food-related stresses and to conditions found within the ... -
Effects of repeated cycles of acid challenge and growth on the phenotype and virulence ofsalmonella enterica
(Wiley-Blackwell, 2008-11-01)Aims: The aim of the study was to investigate how stresses like low pH, which may be encountered in farms or food preparation premises, shape populations of Salmonella enterica by the selection of stress-resistant ... -
Fibronectin-binding proteins are required for biofilm formation by community-associated methicillin-resistantstaphylococcus aureusstrain lac
(Oxford University Press (OUP), 2014-04-01)Community-associated methicillin-resistant Staphylococcus aureus of the USA300 lineage is emerging as an important cause of medical device-related infection. However, few factors required for biofilm accumulation by USA300 ... -
Functional -aminobutyrate shunt in listeria monocytogenes: role in acid tolerance and succinate biosynthesis
(American Society for Microbiology, 2012-10-12)Listeria monocytogenes, the causative agent of human listeriosis, is known for its ability to withstand severe environmental stresses. The glutamate decarboxylase (GAD) system is one of the principal systems utilized by ... -
Loss of sigb in listeria monocytogenes strains egd-e and 10403s confers hyperresistance to hydrogen peroxide in stationary phase under aerobic conditions
(American Society for Microbiology, 2016-05-20)SigB is the main stress gene regulator in Listeria monocytogenes affecting the expression of more than 150 genes and thus contributing to multiple-stress resistance. Despite its clear role in most stresses, its role in ... -
Molecular differentiation of infectious pancreatic necrosis virus isolates from farmed and wild salmonids in ireland
(Wiley-Blackwell, 2009-12-01)This study investigated the genotypes and sub-groups of infectious pancreatic necrosis virus (IPNV) present in farmed and wild salmonid fish in Ireland. An 1100-bp portion of the VP2 region of segment A from each of 55 ... -
Oxacillin alters the toxin expression profile of community-associated methicillin-resistant staphylococcus aureus
(American Society for Microbiology, 2013-12-02)The emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is a growing cause for concern. These strains are more virulent than health care-associated MRSA (HA-MRSA) due to higher levels ... -
Rapid, transient, and proportional activation of b in response to osmotic stress in listeria monocytogenes
(American Society for Microbiology, 2011-09-02)The osmotic activation of sigma B (sigma(B)) in Listeria monocytogenes was studied by monitoring expression of four known sigma(B)-dependent genes, opuCA, lmo2230, lmo2085, and sigB. Activation was found to be rapid, ... -
Redeploying β-lactam antibiotics as a novel antivirulence strategy for the treatment of methicillin-resistantstaphylococcus aureusinfections
(Oxford University Press (OUP), 2016-11-14)Innovative approaches to the use of existing antibiotics is an important strategy in efforts to address the escalating antimicrobial resistance crisis. We report a new approach to the treatment of methicillin-resistant ... -
Role of listeria monocytogenes b in survival of lethal acidic conditions and in the acquired acid tolerance response
(American Society for Microbiology, 2003-05-01)The food-borne pathogen Listeria monocytogenes can acquire enhanced resistance to lethal acid conditions through multiple mechanisms. We investigated contributions of the stress-responsive alternative sigma factor, or ... -
Role of b in regulating the compatible solute uptake systems of listeria monocytogenes: osmotic induction of opuc is b dependent
(American Society for Microbiology, 2003-04-01)The regulation of the compatible solute transport systems in Listeria monocytogenes by the stress-inducible sigma factor sigma(B) was investigated. Using wild-type strain 10403S and an otherwise isogenic strain carrying ... -
Scaffold of selenium nanovectors and honey phytochemicals for inhibition of pseudomonas aeruginosa quorum sensing and biofilm formation
(Frontiers Media SA, 2017-03-23)Honey is an excellent source of polyphenolic compounds that are effective in attenuating quorum sensing (QS), a chemical process of cell-to-cell communication system used by the opportunistic pathogen Pseudomonas aeruginosa ... -
The role of stress and stress adaptations in determining the fate of the bacterial pathogen listeria monocytogenes in the food chain
(Frontiers Media SA, 2016-11-23)The foodborne pathogen Listeria monocytogenes is a highly adaptable organism that can persist in a wide range of environmental and food-related niches. The consumption of contaminated ready-to-eat foods can cause infections, ... -
Thiamine plays a critical role in the acid tolerance of listeria monocytogenes
(Oxford University Press (OUP), 2011-11-14)Understanding the molecular basis of acid tolerance in the food-borne pathogen Listeria monocytogenes is important as this property contributes to survival in the food-chain and enhances survival within infected hosts. The ...