Browsing University of Galway Support Services by Subject "tyrosine-sulfate"

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    • Glycopeptide analogues of psgl-1 inhibit p-selectin in vitro and in vivo 

      Krishnamurthy, Venkata R.; Sardar, Mohammed Y. R.; Ying, Yu; Song, Xuezheng; Haller, Carolyn; Dai, Erbin; Wang, Xiaocong; Hanjaya-Putra, Donny; Sun, Lijun; Morikis, Vasilios; Simon, Scott I.; Woods, Robert J.; Cummings, Richard D.; Chaikof, Elliot L. (Springer Nature, 2015-03-31)
      Blockade of P-selectin (P-sel)/PSGL-1 interactions holds significant potential for treatment of disorders of innate immunity, thrombosis and cancer. Current inhibitors remain limited due to low binding affinity or by the ...