Now showing items 1-2 of 2

    • Oestrogen-dependent regulation of mirna biogenesis: many ways to skin the cat 

      Gupta, Ananya; Caffrey, Emer; Callagy, Grace; Gupta, Sanjeev (Portland Press Ltd., 2012-08-01)
      The steroid hormone oestrogen is central to normal female physiology, reproduction and behaviour, through its effects on cellular processes including cell proliferation and cell survival. The effects of oestrogen are ...
    • Prognostic significance of deregulated dicer expression in breast cancer 

      Caffrey, Emer; Ingoldsby, Helen; Wall, Deirdre; Webber, Mark; Dinneen, Kate; Murillo, Laura S.; Inderhaug, Celine; Newell, John; Gupta, Sanjeev; Callagy, Grace (Public Library of Science (PLoS), 2013-12-30)
      Background: Dicer, an RNase III-type endonuclease, is the key enzyme involved in RNA interference and microRNA pathways. Aberrant expression of Dicer is reported in several human cancers. Our aim was to assess the prognostic ...