Now showing items 1-3 of 3

    • Genotype-dependent responsivity to inflammatory pain: A role for TRPV1 in the periaqueductal grey 

      Madasu, Manish K.; Okine, Bright N.; Olango, Weredeselam M.; Rea, Kieran; Lenihan, Róisín; Roche, Michelle; Finn, David P. (Elsevier, 2016-08-09)
      Negative affective state has a significant impact on pain, and genetic background is an important moderating influence on this interaction. The Wistar-Kyoto (WKY) inbred rat strain exhibits a stress-hyperresponsive, ...
    • Stress-induced hyperalgesia 

      Jennings, Elaine M.; Okine, Bright N.; Roche, Michelle; Finn, David P. (Elsevier, 2014-07-08)
      The importance of the modulation of pain by emotion is now widely recognised. In particular, stress and anxiety, depending on their nature, duration and intensity, can exert potent, but complex, modulatory influences ...
    • Supraspinal Transient Receptor Potential Subfamily V Member 1 (TRPV1) in pain and psychiatric disorders 

      Madasu, Manish K.; Roche, Michelle; Finn, David P. (Karger, 2015)
      The transient receptor potential subfamily V member 1 (TRPV1) belongs to the diverse transient receptor potential (TRP) family of cation channels. It was first characterized in primary afferent fibres as a receptor for ...