Browsing School of Medicine by Subject "Colorectal cancer"

Now showing items 1-3 of 3

    • Impact of mesenchymal stem cell secreted PAI-1 on colon cancer cell migration and proliferation 

      Hogan, Niamh M.; Joyce, Myles R.; Murphy, J. Mary; Barry, Frank P.; O’Brien, Timothy; Kerin, Michael J.; Dwyer, Róisín M. (Elsevier, 2013-05-16)
      Mesenchymal Stem Cells are known to engraft and integrate into the architecture of colorectal tumours, with little known regarding their fate following engraftment. This study aimed to investigate mediators of Mesenchymal ...

    • MicroRNA expression in colorectal cancer. 

      Hogan, Niamh M.; Joyce, Myles R. (IOS Press, 2012-12-17)
      Colorectal cancer is a common disease entity with a multi-factorial aetiology which remains poorly understood. It is estimated that in 2008, colorectal cancerwas responsible for 8% of all cancer deaths, making it the fourth ...

    • Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment 

      Fitzgerald, Seán; Espina, Virginia; Liotta, Lance; Sheehan, Katherine M.; O’Grady, Anthony; Cummins, Robert; O’Kennedy, Richard; Kay, Elaine W.; Kijanka, Gregor S. (BMC (part of Springer Nature), 2018-04-10)
      Background Stromal gene expression patterns predict patient outcomes in colorectal cancer. TRIM28 is a transcriptional co-repressor that regulates an abundance of genes through the KRAB domain family of transcription ...