Browsing School of Medicine by Title
Now showing items 326-336 of 336
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Ulk4 regulates GABAergic signaling and anxiety-related behavior
(Springer Nature, 2018-02-02)Excitation/inhibition imbalance has been proposed as a fundamental mechanism in the pathogenesis of neuropsychiatric and neurodevelopmental disorders, in which copy number variations of the Unc-51 like kinase 4 (ULK4) gene ... -
Urinary sodium and potassium, and risk of ischemic and hemorrhagic stroke (INTERSTROKE): A case–control study
(Oxford University Press, 2020-11-16)Although low sodium intake (3·5g/day) are proposed as public health interventions to reduce stroke risk, there is uncertainty about the benefit and feasibility of this combined recommendation on prevention of stroke and ... -
Using mobile phones to collect patient data: lessons learned from the SIMPle study
(JMIR Publications, 2017-04-25)Background: Mobile phones offer new opportunities to efficiently and interactively collect real-time data from patients with acute illnesses, such as urinary tract infections (UTIs). One of the main benefits of using mobile ... -
Using qualitative insights to change practice: exploring the culture of antibiotic prescribing and consumption for urinary tract infections
(BMJ Publishing Group, 2016-01-11)Objectives: The aim of this paper is to explore the culture of antibiotic prescribing and consumption in the community for urinary tract infections (UTI) from the perspective of the general practitioners (GPs) and community ... -
Validation of an air-puff passive-avoidance paradigm for assessment of aversive learning and memory in rat models of chronic pain
(2012)Chronic pain is associated with cognitive deficits. Considerable overlap in brain regions involved in pain and aversion suggests that aversive learning and memory may be affected during chronic pain. Passive-avoidance ... -
Validation of an air-puff passive-avoidance paradigm for assessment of aversive learning and memory in rat models of chronic pain
(Elsevier, 2011-11)Chronic pain is associated with cognitive deficits. Considerable overlap in brain regions involved in pain and aversion suggests that aversive learning and memory may be affected during chronic pain. Passive-avoidance ... -
The very first requirement of treatment is that it should do no harm†, so why are antibiotics still overprescribed?
(Wiley, 2014-01-26)[No abstract available] -
vIL-10-overexpressing human MSCs modulate naïve and activated T lymphocytes following induction of collagenase-induced osteoarthritis
(2016-05-18)Recent efforts in osteoarthritis (OA) research have highlighted synovial inflammation and involvement of immune cells in disease onset and progression. We sought to establish the in-vivo immune response in collagenase-induced ... -
WestREN: a description of an Irish academic general practice research network
(BioMed Central, 2010-10)Background:Primary care research networks have been established internationally since the 1960s to enable diverse practitioners to engage in and develop research and education and implement research evidence. The newly ... -
When a step is not a step! Specificity analysis of five physical activity monitors
(Public Library of Science, 2017-01-13)IntroductionPhysical activity is an essential aspect of a healthy lifestyle for both physical and mental health states. As step count is one of the most utilized measures for quantifying physical activity it is important ...