Browsing College of Medicine, Nursing and Health Sciences by Author "Dehlfors, Niclas"

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    • The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does not influence revascularization outcome 

      Rossi, Rosanna; Fitzgerald, Sean; Molina, Sara; Mereuta, Oana Madalina; Douglas, Andrew; Pandit, Abhay; Santos, Andreia M. Silva; Murphy, Blathnaid; Alderson, Jack; Brennan, Paul; Power, Sarah; O'Hare, Alan; Gilvarry, Michael; McCarthy, Ray; Psychogios, Klearchos; Magoufis, Georgios; Tsivgoulis, Georgios; Nagy, Andras; Vadasz, Agnes; Szikora, Istvan; Jood, Katarina; Redfors, Petra; Nordanstig, Annika; Ceder, Erik; Dehlfors, Niclas; Dunker, Dennis; Tatlisumak, Turgut; Rentzos, Alexandros; Thornton, John; Doyle, Karen M. (Springer, 2020-09-16)
      Both intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are evidence-based treatments for acute ischemic stroke (AIS) in selected cases. Recanalization may occur following IVT without the necessity of further ...

    • Large artery atherosclerotic clots are larger than clots of other stroke etiologies and have poorer recanalization rates 

      Fitzgerald, Seán; Rossi, Rosanna; Mereuta, Oana Madalina; Molina, Sara; Okolo, Adaobi; Douglas, Andrew; Jabrah, Duaa; Pandit, Abhay; McCarthy, Ray; Gilvarry, Michael; Ceder, Erik; Dehlfors, Niclas; Dunker, Dennis; Nordanstig, Annika; Redfors, Petra; Jood, Katarina; Magoufis, Georgios; Psychogios, Klearchos; Tsivgoulis, Georgios; Alderson, Jack; O’Hare, Alan; Power, Sarah; Brennan, Paul; Nagy, András; Vadász, Ágnes; Brinjikji, Waleed; Kallmes, David; Szikora, Istvan; Tatlisumak, Turgut; Rentzos, Alexandros; Thornton, John; Doyle, Karen M. (Elsevier, 2020-11-24)
      Objectives There is a paucity of knowledge in the literature relating to the extent of clot burden and stroke etiology. In this study, we measured the Extracted Clot Area (ECA) retrieved during endovascular treatment (EVT) ...

    • Per pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted-clot-area and histological composition 

      Fitzgerald, Seán; Rossi, Rosanna; Mereuta, Oana Madalina; Jabrah, Duaa; Okolo, Adaobi; Douglas, Andrew; Molina Gil, Sara; Pandit, Abhay; McCarthy, Ray; Gilvarry, Michael; Dunker, Dennis; Nordanstig, Annika; Ceder, Erik; Redfors, Petra; Jood, Katarina; Dehlfors, Niclas; Magoufis, Georgios; Tsivgoulis, Georgios; Brinjikji, Waleed; Kallmes, David F.; Hare, Alan; Power, Sarah; Brennan, Paul; Alderson, Jack; Nagy, András; Vadász, Ágnes; Psychogios, Klearchos; Szikora, Istvan; Tatlisumak, Turgut; Rentzos, Alexandros; Thornton, John; Doyle, Karen M. (BMJ Publishing Group, 2020-12-09)
      Background Initial studies investigating correlations between stroke etiology and clot composition are conflicting and do not account for clot size as determined by area. Radiological studies have shown that cardioembolic ...

    • Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes 

      Douglas, Andrew; Fitzgerald, Seán; Mereuta, Oana Madalina; Rossi, Rosanna; O'Leary, Sean; Pandit, Abhay; McCarthy, Ray; Gilvarry, Michael; Holmegaard, Lukas; Abrahamsson, Margareta; Jerndal, Mikael; Dehlfors, Niclas; Brennan, Paul; Power, Sarah; O'Hare, Alan; Griffin, Emma; Kallmes, David F.; Brinjikji, Waleed; Szikora, István; Tatlisumak, Turgut; Rentzos, Alexandros; Thornton, John; Doyle, Karen M. (BMJ Publishing Group, 2019-11-04)
      Background and aims Platelets and von Willebrand factor (vWF) are key factors in thrombosis and thus are likely key components of acute ischemic stroke (AIS) emboli. We aimed to characterize platelet and vWF levels in AIS ...