Browsing Physiology by Author "College of Science, National University of Ireland, Galway"
Now showing items 1-3 of 3
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Dose-dependent effects of binge-like methamphetamine dosing on dopamine and neurotrophin levels in rat brain
Moreira da Silva Santos, Andreia; Kelly, John P.; Doyle, Karen M. (Karger Publishers, 2017-10-24)This study investigated the acute effect of a dose range of low-to-moderate binge-like methamphetamine treatments on the regional expression of neurotrophin proteins in the brain and serum 2 h after the last dose, in ... -
Effect of a binge-like dosing regimen of methamphetamine on dopamine levels and tyrosine hydroxylase expressing neurons in the rat brain
Moreira da Silva Santos, Andreia; Kelly, John P.; Dockery, Peter; Doyle, Karen M. (Elsevier, 2018-10-05)Methamphetamine, an amphetamine derivative, is a powerful psychomotor stimulant and commonly used drug of abuse. This study examined the effect of binge-like methamphetamine (MA) dosing (4 x 4 mg/kg, s.c., 2 h apart) on ... -
Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure
Moreira da Silva Santos, Andreia; Gorman, Adrienne M.; Kelly, John P.; Doyle, Karen M. (Elsevier, 2019-11-03)Methamphetamine (MA), a synthetic derivate of amphetamine, has become a major drug of abuse worldwide. This study investigated the effect of binge-like MA dosing (4 x 4 mg/kg, s.c., 2 h (h) apart) at a range of different ...