Browsing Physiology by Author "Cerenovus"
Now showing items 1-6 of 6
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Acute ischemic stroke secondary to cardiac embolus of a ‘foreign body’ material after a redo sternotomy for mitral valve replacement: A case report
Fitzgerald, Seán; Rizvi, Asim; Dai, Daying; Williamson, Eric E.; Lanzino, Giuseppe; Doyle, Karen M.; Kallmes, David F.; Brinjikji, Waleed (SAGE Publications, 2018-11-14)Cardiac surgery has been shown to be associated with increased risk of acute ischemic stroke. This report presents a case of a successful mechanical embolectomy procedure to treat a patient for an acute ischemic stroke, ... -
Does bridging therapy in mechanical thrombectomy increase recanalization rates in ischemic stroke patients affected by acute large vessel occlusion?
Silva Santos, Andreia M.; Rossi, Rosanna; Pandit, Abhay; Fitzgerald, Seán; Mereuta, Oana Madalina; Douglas, Andrew; Thornton, John; Brennan, Paul; Power, Sarah; O’Hare, Alan; Rentzos, Alexandros; Ceder, Erik; Tatlisumak, Turgut; Jood, Katarina; Redfors, Petra; Nordanstig, Annika; Duffy, Sharon; Gilvarry, Michael; McCarthy, Ray; Doyle, Karen M. (SAGE Publications, 2019-05-22)Both intravenous thrombolysis with tissue plasminogen activator (IV-rtPA) and mechanical thrombectomy (MT) increase recanalization rates. We assessed if bridging-therapy (the concomitant use of rtPA and MT) could increase ... -
Histological characterization of white clots retrieved by mechanical thrombectomy from acute ischemic stroke patients
Mereuta, Oana Madalina; Fitzgerald, Seán; Douglas, Andy; Rossi, Rosanna; Silva Santos, Andreia M.; Pandit, Abhay; Thornton, John; Rentzos, Alexandros; Tatlisumak, Turgut; Doyle, Karen M. (SAGE Publications, 2019-01-01)Introduction: Advances in mechanical thrombectomy have created the unique opportunity to study the acute ischemic stroke clot material. However, there is a lack of uniformity in the histopathologic characterization of ... -
Histological stroke clot analysis after thrombectomy: Technical aspects and recommendations
Staessens, S.; Fitzgerald, Seán; Andersson, T.; Clarencon, F.; Denorme, F.; Gounis, M. J.; Hacke, W.; Liebeskind, D. S.; Szikora, I.; van Es, A. C. G. M.; Brinjikji, W.; Doyle, Karen M.; De Meyer, S. F. (SAGE Publications, 2019-11-03)The recent advent of endovascular procedures has created the unique opportunity to collect and analyze thrombi removed from cerebral arteries, instigating a novel subfield in stroke research. Insights into thrombus ... -
The impact of occlusion location and bridging therapy in patients affected by acute ischemic stroke in determining the total number of passes required to remove the clot and the final revascularization outcome
Rossi, Rosanna; Fitzgerald, Seán; Mereuta, Oana Madalina; Douglas, Andrew; Pandit, Abhay; Szikora, István; Tsivgoulis, Georgios; Psychogios, Klearchos; Murphy, Blathnaid; Brennan, Paul; Power, Sarah; O'Hare, Alan; Thornton, John; Rentzos, Alexandros; Tatlisumak, Turgut; Doyle, Karen M. (WFITN (World Federation of Interventional and Therapeutic Neuroradiology), 2019-10-21)Purpose Our purpose was to assess the impact of occlusion location in patients suffering from Acute Ischemic Stroke (AIS) on the total number of passes (attempts) necessary to retrieve the clot and on final revascularization ... -
Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots
Fitzgerald, Seán; Wang, Shunli; Dai, Daying; Murphree Jr, Dennis H.; Pandit, Abhay; Douglas, Andrew; Rizvi, Asim; Kadirvel, Ramanathan; Gilvarry, Michael; McCarthy, Ray; Stritt, Manuel; Gounis, Matthew J.; Brinjikji, Waleed; Kallmes, David F.; Doyle, Karen M. (Public Library of Science, 2019-12-05)Our aim was to assess the utility of a novel machine learning software (Orbit Image Analysis) in the histological quantification of acute ischemic stroke (AIS) clots. We analyzed 50 AIS blood clots retrieved using mechanical ...