Now showing items 1-3 of 3

    • Effects of in vitro endochondral priming and pre-vascularisation of human msc cellular aggregates in vivo 

      Freeman, Fiona E.; Allen, Ashley B.; Stevens, Hazel Y.; Guldberg, Robert E.; McNamara, Laoise M. (Springer Nature, 2015-11-05)
      Introduction: During endochondral ossification, both the production of a cartilage template and the subsequent vascularisation of that template are essential precursors to bone tissue formation. Recent studies have found ...
    • In vitro models for assessing therapeutic angiogenesis 

      Sanz-Nogués, Clara; O'Brien, Timothy (Elsevier, 2016-06-01)
      Arterial obstruction leading to ischemia causes a reduction of oxygen and nutrient supply to distal tissues. The physiological response to tissue ischemia triggers a cascade of events that results in the development of ...
    • Towards in vitro vascularisation of collagen-gag scaffolds 

      Duffy, GP; ,; McFadden, TM; Byrne, EM; Gill, S-L; Farrell, E; O’Brien, FJ (ECM Research Journal, 2011-01-12)
      Collagen-glycosaminoglycan scaffolds that have been used clinically for skin regeneration have also shown significant promise for other applications in tissue engineering. However, regeneration of thicker tissues with the ...