Browsing by Subject "Physiology"
Now showing items 1-7 of 7
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6-iodonordihydrocapsaicin
(2009)6-Iodonordihydrocapsaicin was first synthesized by Giovanni Appendino at the Department of Chemical, Food, Pharmaceutical and Pharmacological Sciences (DiSCAFF), Novara, Italy, while developing a series of halogenated ... -
Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala
(Wiley, 2013-08-29)The association between chronic pain and depression is widely recognized, the comorbidity of which leads to a heavier disease burden, increased disability and poor treatment response. This study examined nociceptive ... -
Circuitry underlying regulation of the serotonergic system by swim stress
(Society for Neuroscience, 2003-02-01)The dorsal raphe nucleus (DR)–serotonin (5-HT) system has been implicated in depression and is dramatically affected by swim stress, an animal model with predictive value for antidepressants. Accumulating evidence implicates ... -
Endocannabinoid regulation of neuroinflammatory responses following acute systemic viral (TLR3) and bacterial (TLR4) infection
(2015-10-14)Toll like receptors (TLRs) are key players in host defence, homeostasis and response to injury. However, uncontrolled and aberrant TLR activation has been proposed to trigger the onset of certain neurodegenerative disorders ... -
Minocycline modulates neuropathic pain behaviour and cortical M1-M2 microglial gene expression in a rat model of depression
(Elsevier, 2014-11)There is a paucity of data on the role of microglia and neuroinflammatory processes in the association between chronic pain and depression. The current study examined the effect of the microglial inhibitor minocycline on ... -
Neuroinflammatory mechanisms linking pain and depression
(Karger, 2015)Depression and chronic pain have been estimated to co-occur in up to 80% of patients suffering from these disorders, with this co-morbidity being more disabling and more expensive to both patients and society than either ... -
Prostaglandin Transport in the Bovine Uterus
(2011-10-20)Abstract In the present study, the effect of bovine oestrous cycle stages and rat oestrous cycle stages were investigated for the expression of PGT protein in uterine tissue, while isolated BUECs were also examined to ...