Now showing items 1-5 of 5

    • Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer 

      Joyce, Doireann (2016-06-15)
      Breast cancer is a heterogeneous group of diseases survival from which depends on stage at diagnosis. The development of blood-based biomarkers which may facilitate earlier detection and possibly subtype delineation remains ...
    • Extracellular vesicles as modulators of wound healing 

      Cabral, Joana; Ryan, Aideen E.; Griffin, Matthew D.; Ritter, Thomas (Elsevier, 2018-01-31)
      Impaired healing of cutaneous wounds and ulcers continues to have a major impact on the quality of life of millions of people. In recent years, the capacity for stem and progenitor cells to promote wound repair has been ...
    • The glycosylation signature of human urinary extracellular vesicles 

      Krueger, Anja (2015-12-22)
      Cells of virtually all organs and tissues are known to release large numbers of subcellular particles called extracellular vesicles (EVs) into bodily fluids such as blood and urine. There has been a growing interest in ...
    • microRNA-mediated intercellular communication in the primary breast tumour microenvironment 

      Glynn, Claire (2014-08-30)
      microRNAs (miRNA) have been highlighted as potential circulating biomarkers and as therapeutic targets for breast cancer. Recent evidence suggests that miRNAs are transported in protective microvesicles called exosomes, ...
    • Screening of exosomal microRNAs from colorectal cancer cells 

      Clancy, Cillian; Khan, Sonja; Glynn, Claire L.; Holian, Emma; Dockery, Peter; Lalor, Pierce; Brown, James A.L.; Joyce, Myles R.; Kerin, Michael J.; Dwyer, Róisín M. (IOS Press, 2017-01-03)
      BACKGROUND: Cells release extracellular membrane vesicles including microvesicles known as exosomes. Exosomes contain microRNAs (miRNAs) however the full range within colorectal cancer cell secreted exosomes is unknown.OBJECTIVE: ...