Browsing by Author "Egan, Laurence"
Now showing items 1-8 of 8
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Analysis and interpretation of epigenomic patterns in colonic epithelia
Barnicle, Alan (2015-12-18)The methylation of cytosine nucleotides at the 5' position of DNA is a crucial epigenetic mechanism for the control of gene expression. Epigenome-wide associated studies have demonstrated that specific methylome patterns ... -
Cellular interactions in the tumour microenvironment during inflammation-associated carcinogenesis
O'Malley, Grace (2017-11-30)The colon tumour microenvironment is highly stromal in composition and a greater stromal cell density correlates with a poor prognosis for patients. The majority of these stromal cells are of mesenchymal origin (MSCs) and ... -
Corrigendum to ‘optimising monitoring in the management of crohn's disease: a physician perspective’ [journal of crohn's and colitis volume 7 (2013) 653–669]
Papay, Pavol; Ignjatovic, Ana; Karmiris, Konstantinos; Amarante, Heda; Miheller, Pal; Feagan, Brian; D'Haens, Geert; Marteau, Philippe; Reinisch, Walter; Sturm, Andreas; Steinwurz, Flavio; Egan, Laurence; Panés, Julián; EdouardLouis,; Colombel, Jean-Frédéric; Panaccione, Remo (Oxford University Press (OUP), 2014-05-01) -
The effects of anti-TNFα antibody therapy on peripheral blood mononuclear cells in patients with inflammatory bowel disease
Slevin, Stephanie (2015-09-30)Monocytes, recently classified as CD14++CD16- (classical), CD14++CD16+ (intermediate) and CD14dimCD16++ (non-classical) are considered to play a role in the pathogenesis of inflammatory bowel diseases (IBD). Anti-tumor ... -
European evidence-based consensus: inflammatory bowel disease and malignancies
Annese, Vito; Beaugerie, Laurent; Egan, Laurence; Biancone, Livia; Bolling, Claus; Brandts, Christian; Dierickx, Daan; Dummer, Reinhard; Fiorino, Gionata; Gornet, Jean Marc; Higgins, Peter; Katsanos, Konstantinos H; Nissen, Loes; Pellino, Gianluca; Rogler, Gerhard; Scaldaferri, Franco; Szymanska, Edyta; Eliakim, Rami; , (Oxford University Press (OUP), 2015-08-20) -
Non-colorectal intestinal tract carcinomas in inflammatory bowel disease: results of the 3rd ecco pathogenesis scientific workshop (ii)
Egan, Laurence; D'Inca, Renata; Jess, Tine; Pellino, Gianluca; Carbonnel, Franck; Bokemeyer, Bernd; Harbord, Marcus; Nunes, Paula; Van der Woude, Janneke; Selvaggi, Francesco; Triantafillidis, John (Oxford University Press (OUP), 2014-01-01) -
Optimising monitoring in the management of crohn's disease: a physician's perspective
Papay, Pavol; Ignjatovic, Ana; Karmiris, Konstantinos; Amarante, Heda; Miheller, Pal; Feagan, Brian; D'Haens, Geert; Marteau, Philippe; Reinisch, Walter; Sturm, Andreas; Steinwurz, Flavio; Egan, Laurence; Panés, Julián; Louis, Edouard; Colombel, Jean-Frédéric; Panaccione, Remo (Oxford University Press (OUP), 2013-09-01) -
Protocol for a multicentred randomised controlled trial investigating the use of personalised golimumab dosing tailored to inflammatory load in ulcerative colitis: the goal-arc study (glm dose optimisation to adequate levels to achieve response in colitis) led by the initiative group (nct 0268772)
Sheridan, Juliette; Coe, Carol Ann; Doran, Peter; Egan, Laurence; Cullen, Garret; Kevans, David; Leyden, Jan; Galligan, Marie; O’Toole, Aoibhlinn; McCarthy, Jane; Doherty, Glen (BMJ, 2018-01-01)Introduction Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD), often leading to an impaired quality of life in affected patients. Current treatment modalities include antitumour necrosis factor (anti-TNF) ...