Browsing by Subject "Drug discovery"
Now showing items 1-4 of 4
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A biological and pharmacological investigation of the unfolded protein response in models of breast cancer
(NUI Galway, 2020-11-20)Breast cancer is the most common malignancy in women worldwide. At the molecular level, breast cancer is a heterogeneous disease. For example, the claudin low subtype of breast cancer is characterised by epithelial-mesenchymal ... -
Improving data workflow systems with cloud services and use of open data for bioinformatics research
(Oxford University Press, 2017-04-16)Data workflow systems (DWFSs) enable bioinformatics researchers to combine components for data access and data analytics, and to share the final data analytics approach with their collaborators. Increasingly, such systems ... -
Irelands’ hidden pharmacy: Marine biodiscovery applied to deep-sea sponges and corals
(NUI Galway, 2022-06-08)Natural products have provided over 60% of our medicines to date, but their search has focused on easy to access habitats, leaving the marine realm underexplored. The deep-sea, which is the world’s largest biome and ... -
Linked Biomedical Dataspace: Lessons Learned integrating Data for Drug Discovery
(Springer, 2014)The increase in the volume and heterogeneity of biomedical data sources has motivated researchers to embrace Linked Data (LD) technologies to solve the ensuing integration challenges and enhance information discovery. As ...