Browsing by Author "Donoghue, Mark T. A."
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High-resolution analysis of parent-of-origin allelic expression in the Arabidopsis endosperm.
Donoghue, Mark T. A.; Spillane, Charles (2011)Genomic imprinting is an epigenetic phenomenon leading to parent-of-origin specific differential expression of maternally and paternally inherited alleles. In plants, genomic imprinting has mainly been observed in the ... -
Microrna-9 inhibition of cell proliferation and identification of novel mir-9 targets by transcriptome profiling in breast cancer cells
Selcuklu, S. Duygu; Donoghue, Mark T. A.; Rehmet, Kristina; de Souza Gomes, Matheus; Fort, Antoine; Kovvuru, Prasad; Muniyappa, Mohan K.; Kerin, Michael J.; Enright, Anton J.; Spillane, Charles (American Society for Biochemistry & Molecular Biology (ASBMB), 2012-07-02)Although underexpression of miR-9 in cancer cells is reported in many cancer types, it is currently difficult to classify miR-9 as a tumor suppressor or an oncomir. We demonstrate that miR-9 expression is down-regulated ...