Browsing by Author "Capoferri, Giuseppina"

Now showing items 1-4 of 4

    • A stromal cell free culture system generates mouse pro-t cells that can reconstitute t-cell compartments in vivo 

      Gehre, Nadine; Nusser, Anja; von Muenchow, Lilly; Tussiwand, Roxane; Engdahl, Corinne; Capoferri, Giuseppina; Bosco, Nabil; Ceredig, Rhodri; Rolink, Antonius G. (Wiley-Blackwell, 2014-12-16)
      T-cell lymphopenia following BM transplantation or diseases such as AIDS result in immunodeficiency. Novel approaches to ameliorate this situation are urgently required. Herein, we describe a novel stromal cell free culture ...

    • Permissive roles of cytokines interleukin-7 and flt3 ligand in mouse b-cell lineage commitment 

      von Muenchow, Lilly; Alberti-Servera, Llucia; Klein, Fabian; Capoferri, Giuseppina; Finke, Daniela; Ceredig, Rhodri; Rolink, Antonius; Tsapogas, Panagiotis (Proceedings of the National Academy of Sciences, 2016-11-29)
      Hematopoietic cells are continuously generated throughout life from hematopoietic stem cells, thus making hematopoiesis a favorable system to study developmental cell lineage commitment. The main factors incorporating ...

    • Permissive roles of cytokines Interleukin-7 and Flt3-ligand in mouse B cell lineage commitment 

      von Muenchow, Lilly; Alberti-Servera, Llucia; Klein, Fabian; Capoferri, Giuseppina; Finke, Daniela; Ceredig, Rhodri; Rolink, Antonius; Tsapogas, Panagiotis (National Academy of Sciences, 2016-11-04)
      Hematopoietic cells are continuously generated throughout life from hematopoietic stem cells, thus making hematopoiesis a favorable system to study developmental cell lineage commitment. The main factors incorporating ...

    • Pro-B cells propagated in stromal cell-free cultures reconstitute functional B-cell compartments in immunodeficient mice 

      von Muenchow, Lilly; Tsapogas, Panagiotis; Albertí-Servera, Llucia; Capoferri, Giuseppina; Doelz, Marianne; Rolink, Hannie; Bosco, Nabil; Ceredig, Rhodri; Rolink, Antonius G. (Wiley, 2016-12-28)
      Up to now long-term in vitro growth of pro-B cells was thought to require stromal cells. However, here we show that fetal liver (FL) and bone marrow (BM) derived pro-B cells can be propagated long-term in stromal cell-free ...