Browsing by Author "Alvarez-Iglesias, Alberto"
Now showing items 1-12 of 12
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Arsenic in groundwater in south west Ireland: Occurrence, controls, and hydrochemistry
McGrory, Ellen; Holian, Emma; Alvarez-Iglesias, Alberto; Bargary, Norma; McGillicuddy, Eoin J.; Henry, Tiernan; Daly, Eve; Morrison, Liam (Frontiers Media, 2018-12-18)Globally numerous regions have been identified with elevated arsenic within groundwater which can result in potential adverse health risks. In Ireland, a previous national-scale research assessment of groundwater identified ... -
Estimating average attributable fractions with confidence intervals for cohort and case control studies
Ferguson, John; Alvarez-Iglesias, Alberto; Newell, John; Hinde, John; O’Donnell, Martin (SAGE Publications, 2016-06-24)Chronic diseases tend to depend on a large number of risk factors, both environmental and genetic. Average attributable fractions were introduced by Eide and Gefeller as a way of partitioning overall disease burden into ... -
Evaluating the feasibility and preliminary efficacy of a Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS): an update to the protocol for a feasibility cluster-randomised controlled trial
Dwyer, Christopher P.; Alvarez-Iglesias, Alberto; Joyce, Robert; Counihan, Timothy J.; Casey, Dympna; Hynes, Sinéad M. (BMC (part of Springer Nature), 2023-01-20)Background Cognitive difficulties experienced by people with multiple sclerosis (MS) impact on quality of life and daily functioning, from childcare and work to social and self-care activities. The Cognitive Occupation-Based ... -
Evaluating the feasibility and preliminary efficacy of a Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS): protocol for a feasibility cluster-randomised controlled trial
Dwyer, Christopher P.; Alvarez-Iglesias, Alberto; Joyce, Robert; Counihan, Timothy J.; Casey, Dympna; Hynes, Sinéad M. (BMC (part of Springer Nature), 2020-03-17)Background Cognitive difficulties experienced by people with multiple sclerosis (MS) impact their quality of life and daily functioning, from childcare and work, to social and self-care activities. Despite the high ... -
An examination of the effects of a patient-designed-and-informed participant information sheet in comparison with a standard, researcher-designed information sheet on recruitment, retention and understanding: Protocol for a study-within-a-trial
Dwyer, Christopher P.; Joyce, Robert A.; Bane, Eimear M.; Moses, Anusha; Alvarez-Iglesias, Alberto; Hynes, Sinéad M. (F1000Research, 2020-01-24)Background: This protocol describes a double-blind, randomised non-inferiority study-within-a-trial (SWAT), comparing the effects of a patient-designed-and-informed participant information sheet with a standard, ... -
Extensions and Applications of Survival Trees in Medical Data
Alvarez-Iglesias, Alberto (2012-09-17)Survival trees are a non-parametric modeling strategy that can be included in the area of statistical modeling. These type of models can be used as an alternative to Cox proportional hazards models for the analysis of ... -
Lipid lowering therapy, low-density lipoprotein level and risk of intracerebral hemorrhage – a meta-analysis
Judge, Conor; Ruttledge, Sarah; Costello, Maria; Murphy, Robert; Loughlin, Elaine; Alvarez-Iglesias, Alberto; Ferguson, John; Gorey, Sarah; Nolan, Aoife; Canavan, Michelle; O'Halloran, Martin; O'Donnell, Martin J. (Elsevier, 2019-03-14)The association of lipid lowering therapy and intracerebral hemorrhage risk is controversial. We performed a cumulative meta-analysis of lipid lowering trials that reported intracerebral hemorrhage. Statin, fibrate, ... -
Remote administration of BICAMS measures and the Trail-Making Test to assess cognitive impairment in multiple sclerosis
Rogers, Fionnuala; Bane, Eimear; Dwyer, Christopher P.; Alvarez-Iglesias, Alberto; Joyce, Robert A.; Hynes, Sinéad M. (Routledge, 2022-03-17)Reliable remote cognitive testing could provide a safer assessment of cognitive impairment in multiple sclerosis (MS) during the COVID-19 pandemic and thereafter. Here we aimed to investigate the reliability and feasibility ... -
SMART MOVE - a smartphone-based intervention to promote physical activity in primary care: study protocol for a randomized controlled trial
Glynn, Liam G.; Hayes, Patrick S.; Casey, Monica; Glynn, Fergus; Alvarez-Iglesias, Alberto; Newell, John; Ó Laighin, Gearóid; Heaney, David; Murphy, Andrew W. (BioMed Central, 2013-05-29)Background: Sedentary lifestyles are now becoming a major concern for governments of developed and developing countries with physical inactivity related to increased all-cause mortality, lower quality of life, and increased ... -
Smart move - a smartphone-based intervention to promote physical activity in primary care: study protocol for a randomized controlled trial
Glynn, Liam G; Hayes, Patrick S; Casey, Monica; Glynn, Fergus; Alvarez-Iglesias, Alberto; Newell, John; ÓLaighin, Gearóid; Heaney, David; Murphy, Andrew W (Springer Nature, 2013-01-01)Background: Sedentary lifestyles are now becoming a major concern for governments of developed and developing countries with physical inactivity related to increased all-cause mortality, lower quality of life, and increased ... -
Summarising censored survival data using the mean residual life function
Alvarez-Iglesias, Alberto; Newell, John; Scarrott, Carl; Hinde, John (Wiley-Blackwell, 2015-01-28) -
Translational statistics and dynamic nomograms
Jalali, Amirhossein (NUI Galway, 2018-03-21)Translational Medicine, within biomedical and public health research domains, is defined as the convergence of basic and clinical research with the aim to transfer knowledge on the benefits and risks of therapies. The ...