Browsing by Subject "toll-like receptors"

Now showing items 1-4 of 4

    • A distinct profile of tryptophan metabolism along the kynurenine pathway downstream of toll-like receptor activation in irritable bowel syndrome 

      Clarke, Gerard; McKernan, Declan P.; Gaszner, Gabor; Quigley, Eamonn M.; Cryan, John F.; Dinan, Timothy G. (Frontiers Media SA, 2012-01-01)
      Irritable bowel syndrome (IBS), a disorder of the brain-gut axis, is characterised by the absence of reliable biological markers. Tryptophan is an essential amino acid that serves as a precursor to serotonin but which can ...

    • Immunological aspects of allogeneic mesenchymal stem cell therapies 

      Griffin, Matthew D.; Ritter, Thomas; Mahon, Bernard P. (Mary Ann Liebert Inc, 2010-12-01)
      Allogeneic mesenchymal stem or stromal cells (MSCs) are proposed as cell therapies for degenerative, inflammatory, and autoimmune diseases. The feasibility of allogeneic MSC therapies rests heavily on the concept that these ...

    • Interaction ofhelicobacter pyloriwith c-type lectin dendritic cell-specific icam grabbing nonintegrin 

      Miszczyk, Eliza; Rudnicka, Karolina; Moran, Anthony P.; Fol, Marek; Kowalewicz-Kulbat, Magdalena; Druszczyńska, Magdalena; Matusiak, Agnieszka; Walencka, Maria; Rudnicka, Wiesława; Chmiela, Magdalena (Hindawi Limited, 2012-01-01)
      In this study we asked whether Helicobacter pylori whole cells and lipopolysaccharide (LPS) utilize sugar moieties of Lewis (Le) antigenic determinants to interact with DC-SIGN (dendritic cell specific ICAM grabbing ...

    • Sterile post-traumatic immunosuppression 

      Islam, Md Nahidul; Bradley, Benjamin A; Ceredig, Rhodri (Springer Nature, 2016-04-29)
      After major trauma, the human immune system initiates a series of inflammatory events at the injury site that is later followed by suppression of local inflammation favoring the repair and remodeling of the damaged tissues. ...