Browsing by Subject "tnf-alpha"
Now showing items 1-7 of 7
-
Antianoikis effect of nuclear factor-κb through up-regulated expression of osteoprotegerin, bcl-2, and iap-1
(American Society for Biochemistry & Molecular Biology (ASBMB), 2006-01-05)Epithelial cells undergo a form of apoptosis termed anoikis when they lose extracellular attachments. We evaluated the role of transcription factor NF-kappa B in the regulation of anoikis susceptibility of intestinal ... -
Carvacrol inhibits osteoclastogenesis and negatively regulates the survival of mature osteoclasts
(Pharmaceutical Society of Japan, 2016-01-01)Bone is a dynamic tissue that undergoes continuous remodeling coupled with the action of osteoblasts and osteoclasts. Osteoclast activity is elevated during osteoporosis and periodontitis resulting in excessive loss of ... -
Changes in the immune system in depression and dementia: causal or co-incidental effects?
(Elsevier BV, 2001-06-01) -
Concise review: adult mesenchymal stromal cell therapy for inflammatory diseases: how well are we joining the dots?
(Wiley-Blackwell, 2013-10-01)Mesenchymal stromal (stem) cells (MSCs) continue to be a strong area of focus for academic- and industry-based researchers who share the goal of expanding their therapeutic use for diverse inflammatory and immune-mediated ... -
Dendritic cells facilitate accumulation of il-17t cells in the kidney following acute renal obstruction
(Elsevier BV, 2008-11-01)Acute urinary obstruction causes interstitial inflammation with leukocyte accumulation and the secretion of soluble mediators. Here we show that unilateral ureteral ligation caused a progressive increase in renal F4/80(+) ... -
Endoplasmic reticulum stress induces ligand-independent tnfr1-mediated necroptosis in l929 cells
(Springer Nature, 2015-01-08)Endoplasmic reticulum (ER) stress-induced cellular dysfunction and death is associated with several human diseases. It has been widely reported that ER stress kills through activation of the intrinsic mitochondrial apoptotic ... -
Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study
(Springer Nature, 2010-05-17)Background: Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance). The majority of newly associated regions encode candidate genes with a ...