Browsing by Subject "tandem repeats"

Now showing items 1-2 of 2

    • A polynucleotide repeat expansion causing temperature-sensitivity persists in wild irish accessions of arabidopsis thaliana 

      Tabib, Amanda; Vishwanathan, Sailaja; Seleznev, Andrei; McKeown, Peter C.; Downing, Tim; Dent, Craig; Sanchez-Bermejo, Eduardo; Colling, Luana; Spillane, Charles; Balasubramanian, Sureshkumar (Frontiers Media SA, 2016-08-31)
      Triplet repeat expansions underlie several human genetic diseases such as Huntington's disease and Friedreich's ataxia. Although such mutations are primarily known from humans, a triplet expansion associated genetic defect ...

    • Birth, evolution, and transmission of satellite-free mammalian centromeric domains 

      Nergadze, Solomon G.; Piras, Francesca M.; Gamba, Riccardo; Corbo, Marco; Cerutti, Federico; McCarter, Joseph G.W.; Cappelletti, Eleonora; Gozzo, Francesco; Harman, Rebecca M.; Antczak, Douglas F.; Miller, Donald; Scharfe, Maren; Pavesi, Giulio; Raimondi, Elena; Sullivan, Kevin F.; Giulotto, Elena (Cold Spring Harbor Laboratory, 2018-04-30)
      Mammalian centromeres are associated with highly repetitive DNA (satellite DNA), which has so far hindered molecular analysis of this chromatin domain. Centromeres are epigenetically specified, and binding of the CENPA ...