Browsing by Subject "internal tandem duplication"
Now showing items 1-2 of 2
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In vivo evidence for an instructive role of fms-like tyrosine kinase-3 (flt3) ligand in hematopoietic development
(Ferrata Storti Foundation (Haematologica), 2014-01-24)Cytokines are essential regulators of hematopoiesis, acting in an instructive or permissive way. Fms-like tyrosine kinase 3 ligand (FLT3L) is an important cytokine for the development of several hematopoietic populations. ... -
Targeting the fms-like tyrosine kinase 3 in acute myeloid leukemia
(Springer Nature, 2012-04-27)Acute myeloid leukemia (AML) is a highly heterogenous disease with multiple signaling pathways contributing to its pathogenesis. A key driver of AML is the FMS-like tyrosine kinase receptor-3 (FLT3). Activating mutations ...