Browsing by Subject "chromosomes"
Now showing items 1-4 of 4
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Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division
(Cold Spring Harbor Laboratory, 2014-01-21)Human cell nuclei are functionally organized into structurally stable yet dynamic bodies whose cell cycle inheritance is poorly understood. Here, we investigate the biogenesis and propagation of nucleoli, sites of ribosome ... -
Dna mediated chromatin pull-down for the study of chromatin replication
(Springer Nature, 2011-09-19)Chromatin replication involves duplicating DNA while maintaining epigenetic information. These processes are critical for genome stability and for preserving cell-type identity. Here we describe a simple experimental ... -
Human replication protein a
(American Society for Biochemistry & Molecular Biology (ASBMB), 2003-02-24)Although the mechanical aspects of the single-stranded DNA (ssDNA) binding activity of human replication protein A (RPA) have been extensively studied, only limited information is available about its interaction with other ... -
Patronus1 is expressed in meiotic prophase i to regulate centromeric cohesion in arabidopsis and shows synthetic lethality with osd1
(Springer Nature, 2015-08-14)Background: Retention of sister centromere cohesion during meiosis I and its dissolution at meiosis II is necessary for balanced chromosome segregation and reduction of chromosome number. PATRONUS1 (PANS1) has recently ...