Browsing by Subject "Unfolded Protein Response"
Now showing items 1-2 of 2
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A biological and pharmacological investigation of the unfolded protein response in models of breast cancer
(NUI Galway, 2020-11-20)Breast cancer is the most common malignancy in women worldwide. At the molecular level, breast cancer is a heterogeneous disease. For example, the claudin low subtype of breast cancer is characterised by epithelial-mesenchymal ... -
Regulation of cell fate by microRNAs during unfolded protein response and its role in cancer
(NUI Galway, 2018-12-20)The endoplasmic reticulum (EnR) stress is a common phenomenon in various cancers such as breast, colorectal, skin and hepatocellular carcinoma. Several pathophysiological events (e.g., radiation, aneuploidy, oncogenic ...