Browsing by Author "Nolan, L."
Now showing items 1-1 of 1
-
Early-stage development of novel cyclodextrin-sirna nanocomplexes allows for successful postnebulization transfection of bronchial epithelial cells
Hibbitts, A.; O'Mahony, A.M.; Forde, E.; Nolan, L.; Ogier, J.; Desgranges, S.; Darcy, R.; MacLoughlin, R.; O'Driscoll, C.M.; Cryan, S.A. (Mary Ann Liebert Inc, 2014-12-01)Background: Successful delivery of small interfering RNA (siRNA) to the lungs remains hampered by poor intracellular delivery, vector-mediated cytotoxicity, and an inability to withstand nebulization. Recently, a novel ...