Browsing by Author "Karatzas, Kimon-Andreas G."
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Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in listeria monocytogenes egd-e and 10403s: roles in virulence and acid tolerance
Feehily, Conor; Finnerty, Aiden; Casey, Pat G.; Hill, Colin; Gahan, Cormac G. M.; O’Byrne, Conor P.; Karatzas, Kimon-Andreas G. (Public Library of Science (PLoS), 2014-11-11)The glutamate decarboxylase (GAD) system has been shown to be important for the survival of Listeria monocytogenes in low pH environments. The bacterium can use this faculty to maintain pH homeostasis under acidic conditions. ... -
Intracellular accumulation of high levels of gamma-aminobutyrate by Listeria monocytogenes 10403S in response to low pH: uncoupling of gamma-aminobutyrate synthesis from efflux in a chemically defined medium
Karatzas, Kimon-Andreas G.; Brennan, Orla; Heavin, Sinead; Morrissey, John J. (American Society for Microbiology, 2010-06)It is well established that the glutamate decarboxylase (GAD) system is central to the survival of Listeria monocytogenes at low pH, both in acidic foods and within the mammalian stomach. The accepted model proposes that ...