Browsing by Author "Horvath, Markus A."

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    • Dynamic actuation enhances transport and extends therapeutic lifespan in an implantable drug delivery platform 

      Whyte, William; Goswami, Debkalpa; Wang, Sophie X.; Fan, Yiling; Ward, Niamh A.; Levey, Ruth E.; Beatty, Rachel; Robinson, Scott T.; Sheppard, Declan; O’Connor, Raymond; Monahan, David S.; Trask, Lesley; Mendez, Keegan L.; Varela, Claudia E.; Horvath, Markus A.; Wylie, Robert; O’Dwyer, Joanne; Domingo-Lopez, Daniel A.; Rothman, Arielle S.; Duffy, Garry P.; Dolan, Eimear B.; Roche, Ellen T. (Nature Research, 2022-08-03)
      Fibrous capsule (FC) formation, secondary to the foreign body response (FBR), impedes molecular transport and is detrimental to the long-term efficacy of implantable drug delivery devices, especially when tunable, temporal ...

    • Soft robotic sleeve supports heart function 

      Roche, Ellen T.; Horvath, Markus A.; Wamala, Isaac; Alazmani, Ali; Song, Sang-Eun; Whyte, William; Machaidze, Zurab; Payne, Christopher J.; Weaver, James C.; Fishbein, Gregory; Kuebler, Joseph; Vasilyev, Nikolay V.; Mooney, David J.; Pigula, Frank A.; Walsh, Conor J. (American Association for the Advancement of Science (AAAS), 2017-01-18)
      There is much interest in form-fitting, low-modulus, implantable devices or soft robots that can mimic or assist in complex biological functions such as the contraction of heart muscle. We present a soft robotic sleeve ...