Browsing by Author "Boyd, Andrew W."
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Anti-gd2-ch14.18/cho coated nanoparticles mediate glioblastoma (gbm)-specific delivery of the aromatase inhibitor, letrozole, reducing proliferation, migration and chemoresistance in patient-derived gbm tumor cells
Tivnan, Amanda; Heilinger, Tatjana; Ramsey, Joanne M.; O'Connor, Gemma; Pokorny, Jenny L.; Sarkaria, Jann N.; Stringer, Brett W.; Day, Bryan W.; Boyd, Andrew W.; Kim, Ella L.; Lode, Holger N.; Cryan, Sally-Ann; Prehn, Jochen H.M. (Impact Journals, LLC, 2017-03-06)Aromatase is a critical enzyme in the irreversible conversion of androgens to oestrogens, with inhibition used clinically in hormone-dependent malignancies. We tested the hypothesis that targeted aromatase inhibition in ...