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Now showing items 12660-12679 of 14646
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Suppression of radiation-induced dna double-strand break repair by myd88 is accompanied by apoptosis and crypt loss in mouse colon
(Springer Nature, 2013-08-01)Intestinal microbes promote the injurious effects of radiation on those tissues. However, the molecular factors mediating this effect are largely unknown. In this work, we explored the effects of orally administered ... -
The suppression-incongruence model of extremism: Investigating extremism through a new lens
(NUI Galway, 2023-01-24)Introduction: Psychological and experimental research is increasingly contributing to our understanding of extremism. This thesis presents and investigates a potentially promising avenue of research in the area of ... -
Supramolecular stacking in a high Z′ calix[8]arene–porphyrin assembly
(Royal Society of Chemistry, 2019-11-15)A co-crystal structure of sulfonato-calix[8]arene (sclx8) and trimethylanilinium-porphyrin (tmap) at 1.0 Å resolution is reported. The oppositely charged macrocycles formed an alternating stacked assembly. Crystal packing ... -
Supramolecular Structures and Tautomerism of Carboxylate Salts of Adenine and Pharmaceutically Relevant N-6-Substituted Adenine
(2011)Co-crystal and salt formation of the kinetin analogue N-6-benzyladenine with the pharmaceutically acceptable co-crystal and salt formers maleic acid, oxalic acid, glutaric acid, succinic acid, benzoic acid, and fumaric ... -
Supramolecular ‘Glues’ for protein recognition and assembly
(NUI Galway, 2019-12-06)Supramolecules such as calixarenes, cucurbiturils and foldamers are rapidly emerging as tools for protein assembly. This thesis builds on past successes with some of these scaffolds. Previously, sulfonato-calix[4]arene was ... -
Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate
(2007)Recent physiological, pharmacological and anatomical studies provide evidence that one of the main roles of the endocannabinoid system in the brain is the regulation of ¿-aminobutyric acid (GABA) and glutamate release. ... -
Supraspinal Transient Receptor Potential Subfamily V Member 1 (TRPV1) in pain and psychiatric disorders
(Karger, 2015)The transient receptor potential subfamily V member 1 (TRPV1) belongs to the diverse transient receptor potential (TRP) family of cation channels. It was first characterized in primary afferent fibres as a receptor for ... -
Supraspinal transient receptor potential subfamily V member 1 (TRPV1) in pain and psychiatric disorders
(Karger, 2015)The transient receptor potential subfamily V member 1 (TRPV1) belongs to the diverse transient receptor potential (TRP) family of cation channels. It was first characterized in primary afferent fibres as a receptor for ... -
Surface acoustic waves in rotating orthorhombic crystals
(The Royal Society, 2004-02-08)The propagation of surface (Rayleigh) waves over a rotating orthorhombic crystal is studied. The crystal possesses three crystallographic axes, normal to the symmetry planes: the half¿space is cut along a plane normal to ... -
Surface chemistry and linker effects on lectin-carbohydrate recognition for glycan microarrays
(2012)Glycan microarrays are an increasingly utilised tool for analysis of protein-carbohydrate interactions and a variety of glycan-containing molecules and slide chemistries have been used to array carbohydrates on microarray ... -
Surface clogging in an intermittent stratified sand filter
(Soil Science Society of America, 2004-01-01)Accumulation of biomass and deposition of suspended solids at the surface of a sand filter can lead to clogging of the filter media. A laboratory intermittent sand filter column, which included three sand strata, was ... -
Surface clogging in an intermittent stratified sand filter.
(Soil Science Society of America Journal, 2004-06-01)Accumulation of biomass and deposition of suspended solids at the surface of a sand filter can lead to clogging of the filter media. A laboratory intermittent sand filter column, which included 3 sand strata, was operated ... -
Surface enhanced Raman scattering for narcotic detection and applications to chemical biology
(Elsevier, 2005)Raman spectroscopy is rapidly finding favour for applications in the life science because of the ease with which it can be used to extract significant data from tissue and cells. However, the Raman effect is an inherently ... -
Surface glycosylation profiles of urine extracellular vesicles
(Public Library of Science (PLoS), 2013-09-19)Urinary extracellular vesicles (uEVs) are released by cells throughout the nephron and contain biomolecules from their cells of origin. Although uEV-associated proteins and RNA have been studied in detail, little information ... -
Surface microstructures on planar substrates and textile fibers guide neurite outgrowth: a scaffold solution to push limits of critical nerve defect regeneration?
(Public Library of Science (PLoS), 2012-12-12)The treatment of critical size peripheral nerve defects represents one of the most serious problems in neurosurgery. If the gap size exceeds a certain limit, healing can't be achieved. Connection mismatching may further ... -
Surface modification of electrodes for enzymatic fuel cell application
(2016-01-07)The immobilisation chemistry of enzymes and redox complexes capable of shuttling electrons between enzymes and electrode surface can have an impact on the magnitude and stability of current response, with implications for ... -
Surface salinity in the north atlantic subtropical gyre during the strasse/spurs summer 2012 cruise
(The Oceanography Society, 2015-03-01)We investigated a 100 x 100 km high-salinity region of the North Atlantic subtropical gyre during the Sub-Tropical Atlantic Surface Salinity Experiment/Salinity Processes in the Upper-ocean Regional Study (STRASSE/SPURS) ... -
Surface stability of nonlinear magnetoelastic solids
(Wiley, 2007-12)The present paper proposes to identify surface stability when a magnetoelastic half-space is subjected to a pure homogeneous pre-deformation and to a magnetic field normal to its (plane) boundary. Clearly, the aim is to ... -
Surface tension prevails over solute effect in organic-influenced cloud droplet activation
(Springer Nature, 2017-06-21)The spontaneous growth of cloud condensation nuclei (CCN) into cloud droplets under supersaturated water vapour conditions is described by classic Kohler theory(1,2). This spontaneous activation of CCN depends on the ...