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The Generation Game: All Gain No Pain? Ageing, Intergenerational Equity and Generational Accounts
(National University of Ireland, Galway, 2002)This paper tries to quantify the degree of intergenerational redistribution in Irish public expenditure. The development of a large public debt in the space of two decades, its rapid elimination and potential rise again ... -
Generation of a panel of high affinity antibodies and development of a biosensor-based immunoassay for the detection of okadaic acid in shellfish
(Elsevier, 2015-07-10)Okadaic acid (OA) and its derivatives, DTX-1 and DTX-2, are marine biotoxins associated with diarrhetic shellfish poisoning. Routine monitoring of these toxins relies on the mouse bioassay. However, due to the technical ... -
Generation of high-affinity chicken single-chain fv antibody fragments for measurement of the pseudonitzschia pungens toxin domoic acid
(American Society for Microbiology, 2006-05-01)Antibody-based assay systems are now accepted by regulatory authorities for detection of the toxins produced by phytoplankton that accumulate in shellfish tissues. However, the generation of suitable antibodies for sensitive ... -
Generation of natural killer cell-mimic nanoparticles to target tumour cells
(NUI Galway, 2022-05-30)Natural killer (NK) cells are effector immune cells in the innate immune system. It is increasingly recognised that NK cells play a crucial role eliminating emerging tumour cells. Some tumour cells however can escape and ... -
Generation of non-bitter casein hydrolysates by using combinations of a proteinase and aminopeptidases
(Portland Press Ltd., 1999-08-01) -
Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity
(Elsevier, 2017-11-03)Nerve growth factor (NGF) is the prototypic member of the neurotrophin family and binds two receptors, TrkA and the 75 kDa neurotrophin receptor (p75NTR), through which diverse and sometimes opposing effects are mediated. ... -
Generation of recombinant anti-N-glycolylneuraminic acid (Neu5Gc) scFv and its applications for detection and quantitation of Neu5Gc
(2016-05-12)Sialic acids are a family of 9 carbon α-keto acid monosaccharides. Owing to their terminal position on glycans, sialic acids are involved in cell adhesion and recognition events, host pathogen interactions, immune regulation ... -
Generational understanding of social support, youth civic engagement and coping as aspects of resilience in socialist and post-socialist Slovenia (1980-2011)
(2015-09-30)This thesis explores the link between protective factors and youth coping as aspects of resilience within the context of social change. The most recent evidence from resilience research shows there is a significant link ... -
Generative Augmented Dataset and Annotation Frameworks for Artificial Intelligence (GADAFAI)
(Institute of Electrical and Electronics Engineers (IEEE), 2020-08-31)Recent Advances in Artificial Intelligence (AI), particularly in the field of compute vision, have been driven by the availability of large public datasets. However, as AI begins to move into embedded devices there will ... -
Generators and relations for the unitary group of a skew hermitian form over a local ring
(Elsevier BV, 2018-04-01)Let (S, *) be an involutive local ring and let U(2m, S) be the unitary group associated to a nondegenerate skew hermitian form defined on a free S-module of rank 2m. A presentation of U(2m, S) is given in terms of Bruhat ... -
Generic principles of effective mental health promotion
(Clifford Beers Foundation, 2007-05)A knowledge base is emerging on the effectiveness of mental health promotion which may be used to guide effective policy and practice. This paper considers the generic principles underpinning the practice of effective ... -
Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons
(Oxford University Press (OUP), 2020-09-25)Myocyte enhancer factor 2 C (MEF2C) is an important transcription factor during neurodevelopment. Mutation or deletion of MEF2C causes intellectual disability (ID) and common variants within MEF2C are associated with ... -
Genes regulated by BCL11B during T‐cell development are enriched for de novo mutations found in schizophrenia patients
(Wiley, 2020-07-29)While abnormal neurodevelopment contributes to schizophrenia (SCZ) risk, there is also evidence to support a role for immune dysfunction in SCZ.BCL11B, associated with SCZ in genome-wide association study (GWAS), is a ... -
The genesis of the Europeanisation of the Northern Ireland peace process
(2018-01-17)The thesis examines the economic and political contributions of the European Union (EU) to the Northern Ireland peace process, tracing the genesis of EU involvement and analysing how it acted as an arena in which to ... -
Genesis of the Moly Brook molybdenum-copper deposit, Newfoundland, Canada: Geological and geochemical constraints on fluid evolution, links with adjacent tungsten mineralization, and the role of Late Devonian granitic intrusions
(NUI Galway, 2017-08-25)An integrated geological, structural and geochemical study of the Moly Brook Mo-Cu deposit, southern Newfoundland (Canada), is presented. The role of subordinate leucogranite as progenitor to the mineralizing components ... -
A genetic algorithm with a multi-layered genotype-phenotype mapping
(SciTePress Digital Library, 2010-08-24)In this paper we investigate the introduction of a multiple-layer genotype-phenotype mapping to a Genetic Algorithm (GA) which attempts to mimic more closely, the effects of nature. The motivation for introducing multiple-layers ... -
Genetic analysis of ATR, a central regulator of genome stability.
(2016-05-11)To protect the DNA against the constant assaults of endogenous and environmental agents, cells have developed conserved signaling pathways, known as the DNA damage response. Such responses are important to maintain genome ... -
Genetic analysis of carotenoid accumulation in tropical maize inbred lines using molecular tools and field tests for accelerating the biofortification of maize with provitamin A
(2015-05-13)Improving the nutritional content of staple crops through breeding (biofortification) is promoted as cheap and sustainable approach for alleviating vitamin A and other micronutrient deficiencies across the world. Maize is ...