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Now showing items 4577-4596 of 14646
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Estimating the value of the benefits of the Marine Strategy Framework Directive
(NUI Galway, 2018-05-11)The European Union introduced the Marine Strategy Framework Directive (MSFD) to ensure that Europe's seas are healthy, clean and productive. To meet these goals, decisions will have to be made and cost and benefits weighed ... -
Estimation and analysis of gene expression and alternative splicing: perspectives from development and disease
(2014-01-30)The development of high-throughput genomics technologies has contributed substantially to the understanding of gene expression regulation. With the growing appreciation of the importance of alternative splicing, quantitative ... -
Estimation of bubble-mediated air–sea gas exchange from concurrent dms and co<sub>2</sub> transfer velocities at intermediate–high wind speeds
(Copernicus GmbH, 2017-07-27)Simultaneous air-sea fluxes and concentration differences of dimethylsulfide (DMS) and carbon dioxide (CO2) were measured during a summertime North Atlantic cruise in 2011. This data set reveals significant differences ... -
Estimation of hydrogen deposition velocities from 1995-2008 at mace head, ireland using a simple box model and concurrent ozone depositions
(Informa UK Limited, 2011-01-01)During stable nocturnal inversions with low wind speeds, we observed strong depletions of both hydrogen and ozone caused by deposition to the peat bogs in the vicinity of the Mace Head Atmospheric Research Station, Connemara, ... -
Estimation of mackerel ( l., 1758) and horse mackerel ( l., 1758) daily egg production outside the standard ices survey area
(Oxford University Press (OUP), 2005-12-01) -
Estimation of Maximum Biosolids and Meat and Bone Meal Application to a Low P Index Soil and a Method to Test for Nutrient and Metal Losses
(2013)The aim of this study was to develop (1) a method for the calculation of the maximum legal rate at which meat and bone meal (MBM) and biosolids should be applied to land, which took into account the soil phosphorus (P) ... -
Estimation of sea-surface wind speed from whitecap cover: statistical approaches compared empirically and by simulation
(Informa UK Limited, 1986-08-01) -
Estimation of the impact of CAP reform on the structure of farming in the disadvantaged areas of Ireland
(National University of Ireland, Galway, 1997-09)In this paper the Johansen model was used to examine the impact of CAP Reform on the structure of farming in the Disadvantaged Areas of Ireland. The model is essentially a policy impact model using an elasticity set. ... -
Estrogen deficiency alters the mechanobiological responses of osteoblasts and osteocytes
(NUI Galway, 2020-07-03)Osteoporosis is most commonly manifested following menopause when estrogen production is deficient and, as a result, bone loss and changes in bone composition occur leading to bone fractures. Estrogen inhibits bone ... -
estrogen deficiency attenuates fluid flow–induced [ca 2+ ] i oscillations and mechanoresponsiveness of mlo-y4 osteocytes
(FASEB, 2017-03-31)It has been proposed that estrogen regulates the mechanosensitivity of osteocytes; however, the effects of estrogen deficiency that arises during postmenopausal osteoporosis on mechanical stimulation induced calcium signaling ... -
Estrogen deficiency impairs integrin αvβ3-mediated mechanosensation by osteocytes and alters osteoclastogenic paracrine signalling
(Nature Research (part of Springer Nature), 2019-03-15)The integrin alpha(v)beta(3) has been shown to play an important role in osteocyte mechanotransduction. It has been reported that there are fewer beta(3) integrin-containing cells in osteoporotic bone cells. Osteocytes ... -
Estrogen induces repression of the breast cancer and salivary gland expression gene in an estrogen receptor dependent manner
(American Association for Cancer Research (AACR), 2008-01-01)The focus of this study is on the expression and regulation of the estrogen-regulated breast cancer and salivary gland expression (BASE) gene that may function as a breast cancer marker. In MCF7 cells, BASE is repressed ... -
Estrogen plus estrogen receptor antagonists alter mineral production by osteoblasts in vitro
(Thieme Publishing Group, 2011-11-28)In early postmenopausal women, estrogen withdrawal is associated with increased bone turnover leading to bone loss and increased risk of fracture. Recent studies have suggested that the remaining bone tissue is significantly ... -
Estrogen withdrawal in osteocytes results in altered integrin function, primary cilium elongation, and increased pro-osteoclastogenic signalling
(NUI Galway, 2020-06-28)Osteocytes are the main mechanosensitive cells within bone. They detect changes in the mechanical environment and transduce them into biochemical responses (RANKL, OPG, and sclerostin) that regulate bone remodelling by ... -
Estrogen withdrawal, increased breast cancer risk and the kras-variant
(Informa UK Limited, 2015-05-11)The KRAS-variant is a biologically functional, microRNA binding site variant, which predicts increased cancer risk especially for women. Because external exposures, such as chemotherapy, differentially impact the effect ... -
Ethical challenges in qualitative research: Examples from practice
(RCN Publishing Ltd., 2010-10-22)This article examines the many ethical challenges that are specific to qualitative research. These challenges concern the issues of informed consent procedures, the researcher-participant relationship, risk-benefit ratio, ... -
An ethical commitment: responsibility, cosmopolitanism and care in the internationalised university
(Routledge, 2013-10)The internationalization of higher education has decisively moved from being a scholarly tradition of mobility across borders to an almost purely economic concern. This is a trend that is most pronounced in countries such ... -
Ethical dilemmas in the development-security nexus: A human development and capabilities approach
(Centre for Global Education, 2019)The development-security nexus marks a paradigm shift for development, security and humanitarian practice, with implications for education and development education. This article explores zigzag changes, initially towards ... -
Ethical Issues in Internet Research: International Good Practice and Irish Research Ethics Documents
(Research-publishing.net, 2013)This chapter discusses the main research ethical concerns that arise in internet research and reviews existing research ethical guidance in the Irish context in relation to its application to internet research. The ...