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Now showing items 4364-4383 of 14646
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The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential.
(SAGE, 2012-01)Although the pharmacological and medicinal properties of the plant Cannabis sativa have long been known and appreciated, the discovery of the endocannabinoid system began with the isolation of [delta]9-tetrahydrocannabinol ... -
The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nocicpetive tone
(Wiley, 2011)Background and purpose: Endocannabinoids in the midbrain periaqueductal grey (PAG) are involved in modulating nociception and unconditioned stress-induced analgesia, however, their role in fear-conditioned analgesia (FCA) ... -
Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: Opioid receptor dependency and molecular correlates
(International Association for the Study of Pain, 2008-12)The opioid and endocannabinoid systems mediate analgesia expressed upon re-exposure to a contextually aversive stimulus (fear-conditioned analgesia; FCA), and modulate the mitogen-activated protein kinase (MAPK) pathway. ... -
EndoCOM : Conception d un banc in vitro de simulation des anévrismes de l aorte abdominale
(2009)(FR) Le traitement des anévrismes de l'aorte abdominale par voie endovasculaire est aujourd'hui prédominant à plus de 65 % mais comporte encore des risques. Le suivi postopératoire devient alors crucial. Le projet de ... -
ENDOCOM: Abdominal aortic aneurysm test bench for in vitro simulation
(IEEE, 2007)An abdominal aortic aneurysm (AAA) is a dilatation of the aorta at the abdominal level, whose rupture is a life threatening complication. Recent treatment procedures of AAA consists in endovascular treatment with covered ... -
Endometrial gene expression in high- and low-fertility heifers in the late luteal phase of the estrous cycle and a comparison with midluteal gene expression
(American Physiological Society, 2016-02-05)Embryonic mortality is a major constraint to improving reproductive efficiency and profitability in livestock enterprises. We previously reported differential expression of genes with identified roles in cellular growth ... -
Endopeptidase activities ofstreptococcus cremoris
(Portland Press Ltd., 1990-04-01) -
Endoplasmic reticulum stress and the unfolded protein response: targeting the achilles heel of multiple myeloma
(American Association for Cancer Research (AACR), 2013-05-31)Multiple myeloma is characterized by the malignant proliferating antibody-producing plasma cells in the bone marrow. Despite recent advances in therapy that improve the survival of patients, multiple myeloma remains incurable ... -
Endoplasmic Reticulum Stress as a Component of Demyelination in Animal Models of Multiple Sclerosis
(2012-12-19)Endoplasmic reticulum (ER) stress is a homeostatic signalling pathway, linked to many neurological diseases including multiple sclerosis (MS), which can lead to cell death when prolonged. Increasing evidence suggests that ... -
Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells
(2015)Endoplasmic reticulum (ER) stress-induced cellular dysfunction and death is associated with several human diseases. It has been widely reported that ER stress kills through activation of the intrinsic mitochondrial apoptotic ... -
Endoplasmic reticulum stress induces ligand-independent tnfr1-mediated necroptosis in l929 cells
(Springer Nature, 2015-01-08)Endoplasmic reticulum (ER) stress-induced cellular dysfunction and death is associated with several human diseases. It has been widely reported that ER stress kills through activation of the intrinsic mitochondrial apoptotic ... -
Endoplasmic reticulum stress signalling in myelination
(2017-12-07)Demyelinating conditions such as multiple sclerosis have a continued unmet need for remyelinating therapies. Myelin is a multi-lamellar membrane structure made by oligodendrocyte progenitor cells (OPCs) that is critical ... -
Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis
(American Association for Cancer Research (AACR), 2015-05-14) -
Endoplasmic reticulum stress-mediated induction of sestrin 2 potentiates cell survival
(Impact Journals, LLC, 2016-02-22)Upregulation of SESTRIN 2 (SESN2) has been reported in response to diverse cellular stresses. In this study we demonstrate SESTRIN 2 induction following endoplasmic reticulum (ER) stress. ER stress-induced increases in ... -
Endoplasmic reticulum stress: at the crossroads of inflammation and metabolism in hepatocellular carcinoma development
(Elsevier BV, 2014-09-01)Steatohepatitis is a cause of hepatocellular carcinoma development; however, the underlying mechanisms are poorly defined. In this issue of Cancer Cell, Nakagawa and colleagues demonstrate that activation of endoplasmic ... -
Endoscopic resection of nasopharyngeal angiofibroma: The role of radio-frequency coblation
(PagePress, 2011-08-29)Nasopharyngeal angiofibromas are histologically benign but locally aggressive vascular tumors that can result in major morbidity and mortality. They exclusively affect adolescent male and are rare in patients older than ... -
Endosymbiosis undone by stepwise elimination of the plastid in a parasitic dinoflagellate
(Proceedings of the National Academy of Sciences, 2015-04-20)Organelle gain through endosymbiosis has been integral to the origin and diversification of eukaryotes, and, once gained, plastids and mitochondria seem seldom lost. Indeed, discovery of nonphotosynthetic plastids in many ... -
Endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B ) in human arterial smooth muscle cells
(Elsevier, 2015-12-01)Endothelial nitric oxide synthase (eNOS) is the major source of nitric oxide (NO) production in blood vessels. One of the pleitropic functions of eNOS derived NO is to inhibit vascular smooth muscle cell proliferation ...