Browsing by Title
Now showing items 3858-3877 of 14646
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Drug resistance, evolution and diversity of HIV-1 in Malawi
(2012-09-07) -
Drug target discovery using knowledge graph embeddings
(Association for Computing Machinery, 2019-04-08)The field of drug discovery has entered a plateau stage lately. It is increasingly more expensive and time-demanding to introduce new drugs into the market. One of the main reasons is the slow progress in finding novel ... -
Drugging the unfolded protein response in acute leukemias
(Springer Nature, 2015-07-16)The unfolded protein response (UPR), an endoplasmic reticulum (ER) stress-induced signaling cascade, is mediated by three major stress sensors IRE-1 alpha, PERK, and ATF6 alpha. Studies described the UPR as a critical ... -
The Drugs Don't Work
(The Irish Times, 2005-01-15) -
Druid Theatre’s Leenane Trilogy on tour: 1996–2001
(Carysfort Press, 2005-09-20)[No abstract available] -
A dual image processing pipeline camera with CE applications
(2011)The implementation of a dual image processing pipeline camera on a state-of-art FPGA system is described. This camera can simultaneously acquire dual images of a scene and process, analyze and merge both images to enable ... -
Dual ire1 rnase functions dictate glioblastoma development
(EMBO, 2018-01-08)Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Evidence suggests that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical ... -
Dual-drug amorphous formulation of gliclazide
(Taylor and Francis, 2021-02-01)Amorphization is a well-established strategy to enhance the dissolution properties of poorly water-soluble drugs. However, the amorphous state is inherently unstable toward recrystallization. Coamorphous systems of a drug ... -
Dual-phase cohesive zone modelling and experimental validation for hydrogen-assisted cracking of 2205 duplex stainless steel
(Elsevier, 2021-01-01)The hydrogen-assisted cracking (HAC) behavior of 2205 duplex stainless steel is investigated via experimental testing and computational modelling, with specific focus on developing a predictive methodology for the coupled ... -
The duality of e-participation - a model and technical infrastructure to study and harness social media-based participation
(2016-10-21)Despite the proliferation of e-Participation initiatives, overall efforts towards mainstreaming social media-based and citizen-led political deliberations are still limited. Consequently, there is a paucity of research on ... -
Dublin City University and Partners' participation in the INS and VTT Tracks at TRECVid 2016
(2016-11-14)Dublin City University participated with a consortium of colleagues from NUI Galway and Universitat Polit`ecnica de Catalunya in two tasks in TRECVid 2016, Instance Search (INS) and Video to Text (VTT). For the INS task ... -
The Dublin Group: Irish mezzotint printmakers and the Dublin print trade c. 1740 to 1750
(2015-05-25)This thesis explores the unique cultural and historical conditions leading to mezzotint portrait reproduction in Dublin during the 1740s. Arguably, the experiences and activity of the Dublin Group at Cork Hill facilitated ... -
Ductus arteriosus aneurysm presenting as hoarseness: successful repair with an endovascular approach
(Oxford University Press (OUP), 2016-04-01)An aneurysm of the ductus arteriosus is a rare finding, particularly in the adult population. These saccular aneurysms arise at the site of an incompletely obliterated ductus arteriosus along the lesser curvature of the ... -
Duragraft vascular conduit preservation solution in patients undergoing coronary artery bypass grafting: rationale and design of a within-patient randomised multicentre trial
(BMJ, 2018-04-01)Introduction Saphenous vein grafts (SVGs) remain the most often used conduits in coronary artery bypass grafting (CABG). However, they are prone to vein graft disease (VGD) during follow-up, which may compromise clinical ... -
Dúchas agus iasacht san amhránaíocht thraidisiúnta faoi réir chás-staidéar ar phobal Charna
(NUI Galway, 2019-09-25)Déantar iniúchadh sa tráchtas seo ar ghnéithe d’amhránaíocht thraidisiúnta na Gaeilge nó an amhránaíocht ar an sean-nós mar a thugtar go coitianta uirthi. Is do choincheapa an dúchais agus na hiasachta a thugtar tús áite ... -
Dúshláin agus deiseanna i gcur i bhfeidhm an Phlean Teanga i Limistéar Pleanála Teanga (LPT) Ghaeltacht na Mí
(Acadamh na hOllscolaíochta Gaeilge, Ollscoil na hÉireann, Gaillimh, 2020)Is léirmheas ar roinnt dúshlán agus deiseanna i gcur i bhfeidhm an Phlean Teanga i Limistéar Pleanála Teanga (LPT) Ghaeltacht na Mí é seo. Chuige sin, pléitear leagan amach an LPT; an Coiste Stiúrtha agus Pleanáil Áitiúil ... -
Dyadic concordance in mother and preschooler resting cardiovascular function varies by risk status
(Wiley-Blackwell, 2013-09-11) -
Dying well: factors that influence the provision of good end-of-life care for older people in acute and long-stay care settings in Ireland
(2011)Aim: The aim of this study was to explore key stakeholders and direct care managers' perspectives on the current provision of end-of-life care for older people in acute and long-stay care settings in Ireland and to construct ... -
Dyke-davidoff-masson syndrome presenting with bipolar i mania with psychosis
(Medknow, 2018-01-01) -
Dynamic actuation enhances transport and extends therapeutic lifespan in an implantable drug delivery platform
(Nature Research, 2022-08-03)Fibrous capsule (FC) formation, secondary to the foreign body response (FBR), impedes molecular transport and is detrimental to the long-term efficacy of implantable drug delivery devices, especially when tunable, temporal ...