Browsing by Title
Now showing items 3425-3444 of 14646
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Development of a feasible implementation fidelity protocol within a complex physical therapy-led self-management intervention
(Oxford University Press, 2016-08-01)Implementation fidelity is poorly addressed within physical therapy interventions, which may be due to limited research on how to develop and implement an implementation fidelity protocol. The purpose of this study was ... -
Development of a flow cytometry-based potency assay for measuring the in vitro immunomodulatory properties of mesenchymal stromal cells
(Elsevier, 2016-07-20)Human bone marrow-derived mesenchymal stromal/stem cells (MSC) have well-documented modulatory effects on multiple immune cell types. Although these effects are linked to their therapeutic benefit in diverse diseases, a ... -
Development of a framework for activation of aggregator led flexibility
(MDPI, 2021-08-12)This paper presents a novel framework architecture for an online, real¿time flexibility as¿ sessment and activation platform targeted at unlocking the flexibility potential of commercial build¿ ings and smaller industrial ... -
Development of a fundus camera with adaptive optics using a pyramid wavefront sensor
(2012-03-02)This PhD thesis presents the building of an adaptive-optics system based on a pyramid wavefront sensor applied to the imaging of the human retina (fundus) in vivo. The instrument aims to simultaneaously measure the ocular ... -
Development of a gene-eluting stent for the treatment of in-stent restenosis
(2016-05-12)In-stent restenosis (ISR) results from stent-induced arterial injury, characterized by a complex cascade of cellular and biochemical events. The removal of endothelium during an angioplasty procedure causes the underlying ... -
Development of a global energy management system (GEMS) for the life sciences industry
(NUI Galway, 2015-08)For multi-national companies, assessment of cost effective energy efficiency projects across a global site base is a complex problem involving multiple variables. This research project proposes a novel methodology for ... -
Development of a Global Energy Management System for non-energy intensive multi-site industrial organisations: A methodology
(Elsevier, 2017-01-25)For multi-site organisations, informed decision making on capital investment aimed at improving energy performance and cutting carbon emissions, across a global site base, is a complex problem. This work presents the ... -
Development of a global energy management system for the life sciences industry: an energy management maturity model implementation
(NUI Galway, 2015-11)The Global Energy Management System (GEMS) research project proposes a novel methodology for assessing capital energy-efficiency projects at a global level. The paper scope covers the systematic development and implementation ... -
Development of a global energy management system for the non-energy intensive multi-site manufacturing organisations
(NUI Galway, 2018-09-30)Climate change and energy resource sustainability are both major challenges facing humanity today. Due to their scale, multi-site (and/or multi-national) manufacturing organisations (MMO), are large consumers of energy, ... -
Development of a high throughput screening strategy for drug discovery: from marine fungi to stem cell applications
(NUI Galway, 2021-08-04)Chemical compounds synthetized by living organisms have historically contributed to improved human health. Ancient populations made use of local natural products through herbal medicine, which today are to be found as ... -
Development of a high time resolution optical polarimeter for astronomy
(NUI Galway, 2018-12-17)This work started in September, 2014 and initially started as an investigation of the characterisation issues associated with using Electron Multiplying Charge- Coupled Devices (EMCCDs) in a two beam polarimeter. It was ... -
Development of a high-resolution gamma-ray imaging system with synthetic collimation.
(2013-11-01)This work outlines the development of a multi-pinhole single-photon emission computed tomography (SPECT) system designed to produce a synthetic-collimator image of a small field of view. The synthetic-collimator image was ... -
The development of a high-resolution nested bridge hydraulic model
(NUI Galway, 2023-11-23)Traditionally, hydraulic modelling of bridges has been undertaken using one dimensional models like HEC-RAS. One-dimensional models simplify river channels using several cross sections along a river curve and strongly ... -
Development of a joint hydrogen and syngas combustion mechanism based on an optimization approach
(Wiley, 2016-05-20)A comprehensive and hierarchical optimization of a joint hydrogen and syngas combustion mechanism has been carried out. The Keromnes et al. (Combust Flame, 2013, 160, 995-1011) mechanism for syngas combustion was updated ... -
The development of a lean six sigma and BIM framework for enhancing off-site manufacturing
(Emerald, 2023-05-12)This project aims to improve a construction company's overall project delivery by utilising Lean Six sigma methods combined with Business Information Modeling (BIM) to design, modularise and manufacture various building ... -
Development of a mesenchymal stromal cell / collagen scaffold product for treatment of diabetic wounds
(NUI Galway, 2022-08-23)Foot ulceration is a major complication of diabetes mellitus, which results in significant human suffering and a major burden on healthcare systems. Mesenchymal stromal cells (MSCs) emerged as a promising therapeutic ... -
Development of a microgel-based cell delivery platform for critical limb ischemia
(2017-05-05)Peripheral Arterial Diseases (PAD) is a chronic and debilitating disease caused due to narrowing and hardening of arteries, that results in progressive deterioration of blood flow to the limbs. PAD commonly occurs in the ... -
Development of a mixed glial in vitro robust platform for therapeutic applications in spinal cord injury
(NUI Galway, 2021-06-30)Spinal cord injury (SCI) is a catastrophic event, and current strategies for SCI pose several limitations. One of the critical hallmarks of SCI is inflammation, which is due to the activation of microglia and astrocytes. ... -
Development of a nested 3D hydrodynamic model for tidal turbine impact assessment
(2016-05-12)Tidal current energy resources have the potential to provide a sizable proportion of our future energy requirements. However, significant questions still exist on the impacts of tidal turbines on the hydrodynamic environment. ... -
Development of a nested coastal circulation model: boundary error reduction
(Elsevier, 2014-03)Numerical models have a valuable role to play in the sustainable management of coastal waters but accurate simulation of land/sea interactions, particularly in areas of complex coastlines, requires the use of high spatial ...