Browsing by Author "Science Foundation Ireland"
Now showing items 41-60 of 272
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Development and Implementation of an Ultra High Speed Astronomical Polarimeter: The Galway Astronomical Stokes Polarimeter (GASP)
Collins, Patrick P. (2013-05-12)Optical polarization is a powerful diagnostic tool in astrophysics, allowing the investigation of asymmetries in source regions of astronomical objects, magnetic field configurations, and magnetic field strengths. Polarized ... -
Development of a dual-hit model of Parkinson's disease by combining environmental and genetic risk factors
Mulcahy, Pádraig John (2012-06-06)Even though half a century has passed since the discovery of the efficacy of the dopamine precursor, levodopa, it remains the most effective therapy for the motor symptoms of Parkinson's disease to this day, despite its ... -
Development of a microgel-based cell delivery platform for critical limb ischemia
Thomas, Dilip (2017-05-05)Peripheral Arterial Diseases (PAD) is a chronic and debilitating disease caused due to narrowing and hardening of arteries, that results in progressive deterioration of blood flow to the limbs. PAD commonly occurs in the ... -
The Development of A Realistic Simulation Framework with OMNeT++
Shu, Lei (IEEE, 2008)It is necessary to use simulation tools in the study of wireless network. The object-oriented modular discrete event network simulator, OMNeT++, can not only afford many network simulation but has strong GUI support and ... -
Development of a targeting mechanism for regeneration of the intervertebral disc
Cunningham, Claire (2014-11-24)Degeneration of the intervertebral discs (IVD) is a leading cause of neck and low back pain. While its aetiology is poorly understood, it is known to begin in the central nucleus pulposus region, leading to degradation of ... -
Development of novel nucleic acid diagnostics technologies for the detection of predominant microorganisms associated with bacterial meningitis
Coughlan, Helena (2017-01-13)With an estimated 1.2 million cases annually worldwide, bacterial meningitis is a medical emergency and primary prevention as well as accurate diagnosis and treatment of this often fatal disease is paramount. The ... -
The Development of Ultra Wideband Scanning Techniques for Detection and Classification of Breast Cancer
Conceicao, Raquel (2010-09-30)This thesis addresses the development of imaging techniques for the early detection of breast cancer, based on Ultra Wideband (UWB) radar, a promising emerging technology that exploits the dielectric contrast between normal ... -
Dielectric characterization of diseased human trabecular bones at microwave frequency
Amin, Bilal; Shahzad, Atif; Farina, Laura; Parle, Eoin; McNamara, Laoise; O'Halloran, Martin; Elahi, Muhammad Adnan (Elsevier, 2020-02-07)The objective of this study is to determine whether in vitro dielectric properties of human trabecular bones, can distinguish between osteoporotic and osteoarthritis patients' bone samples. Specifically this study enlightens ... -
DigiMe - Ubiquitous Search and Browsing for Digital Libraries
Kruk, Sebastian Ryszard; Grzonkowski, Slawomir; Gzella, Adam; Cygan, Mariusz (IEEE, 2006)Vast sources of information, such as the Internet are difficult to browse and/or search through. Existing tools can be sometimes frustrating for many people. So far a number of techniques have been proposed to deliver ... -
DING! Dataset Ranking using Formal Descriptions
Toupikov, Nickolai; Umbrich, Jürgen; Delbru, Renaud; Hausenblas, Michael; Tummarello, Giovanni (2009)Considering that thousands if not millions of linked datasets will be published soon, we motivate in this paper the need for an efficient and effective way to rank interlinked datasets based on formal descriptions of their ... -
Discovery of Optimized Web Service Configurations Using a Hybrid Semantic and Statistical Approach
Zaremba, Maciej; Migdal, Jacek; Hauswirth, Manfred (IEEE, 2009)We present a Semantic Optimized Service Discovery (Se- mOSD) approach capable of handling Web service search requests on a fine-grained level of detail where we augment semantic service descriptions with statistically built ... -
A dislocation mechanics constitutive model for effects of welding-induced microstructural transformation on cyclic plasticity and low-cycle fatigue for X100Q bainitic steel
Devaney, Ronan J.; Barrett, Richard A.; O'Donoghue, Padraic E.; Leen, Sean B. (Elsevier, 2020-12-14)This paper presents a physically-based cyclic viscoplasticity model to capture the influence of welding-induced microstructural transformation on the fatigue response of the bainitic high-strength low-alloy steel, X100Q. ... -
A dislocation-based yield strength determination model in nano-indentation test
Tao, Ping; Ye, Fei; Gong, Jianming; Barrett, Richard A.; Leen, Sean B. (SAGE Publications, 2021-02-20)This paper presents a dislocation-based yield strength model for the nano-indentation size effect. The model is based on functional expressions involving the densities of statistically stored dislocations and geometrically ... -
Dissecting the pan-placodal gene regulatory network reveals novel interactions driving sense organ development in vertebrates
Riddiford, Nick (2016-02-17)The genes encoding the transcription factor Six1, and its co-factor Eya1 together mark the embryonic territory - the pan-placodal ectoderm (PPE) - that gives rise to most cranial sense organs in vertebrates. Mutation of ... -
A Distributed Semantic Microblogging Platform
Passant, Alexandre; Hastrup, Tuukka; Bojars, Uldis; Breslin, John (2008)The application showcases the ideas of a distributed, Semantic-Web enabled micro blogging architecture, providing a way to leverage this new Web 2.0 practice to the Semantic Web. -
dlvhex-sparql: A SPARQL-compliant query engine based on dlvhex
Polleres, Axel (CEUR, 2007)This paper describes the dlvhex SPARQL plugin, a query processor for the upcoming Semantic Web query language standard by W3C. We report on the implementation of this languages using dlvhex, a flexible plugin system ... -
DNA mediated chromatin pull-down for the study of chromatin replication
Kliszczak, Anna E.; Rainey, Michael D.; Harhen, Brendan; Santocanale, Corrado (2011)Chromatin replication involves duplicating DNA while maintaining epigenetic information. These processes are critical for genome stability and for preserving cell-type identity. Here we describe a simple experimental ... -
DNA mediated chromatin pull-down: a novel method for the study of chromatin replication
Kliszczak, Anna Ewelina (2012-04-27)Chromatin replication involves duplicating DNA while maintaining epigenetic information. These processes are critical for genome stability and for preserving cell-type identity. To investigate how these processes are ... -
Dual-drug amorphous formulation of gliclazide
Aljohani, Marwah; McArdle, Patrick; Erxleben, Andrea (Taylor and Francis, 2021-02-01)Amorphization is a well-established strategy to enhance the dissolution properties of poorly water-soluble drugs. However, the amorphous state is inherently unstable toward recrystallization. Coamorphous systems of a drug ... -
Dual-phase cohesive zone modelling and experimental validation for hydrogen-assisted cracking of 2205 duplex stainless steel
Tao, Ping; Ye, Fei; Gong, Jianming; Yang, Xinyu; Barrett, Richard A.; Leen, Sean B. (Elsevier, 2021-01-01)The hydrogen-assisted cracking (HAC) behavior of 2205 duplex stainless steel is investigated via experimental testing and computational modelling, with specific focus on developing a predictive methodology for the coupled ...