ARAN: Recent submissions
Now showing items 1-20 of 12373
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Supramolecular stacking in a high Z′ calix[8]arene–porphyrin assembly
(Royal Society of Chemistry, 2019-11-15)A co-crystal structure of sulfonato-calix[8]arene (sclx8) and trimethylanilinium-porphyrin (tmap) at 1.0 Å resolution is reported. The oppositely charged macrocycles formed an alternating stacked assembly. Crystal packing ... -
Urothelial carcinoma: Molecular profiling and potential application in clinical practice
(NUI Galway, 2020-02-19)Urothelial Carcinoma: Molecular Profiling & Potential Application in Clinical Practice Abstract Introduction: Urothelial carcinoma is characterised by a tendency to recurrence and risk of progression that necessitates ... -
Global and local tests to assess stationarity of Markov transition models
(Taylor & Francis, 2018-02-09)We present global and local likelihood-based tests to evaluate stationarity in transition models. Three motivational studies are considered. A simulation study was carried out to assess the performance of the proposed ... -
A Weibull-count approach for handling under- and overdispersed longitudinal/clustered data structures
(SAGE Publications, 2018-07-30)A Weibull-model-based approach is examined to handle under- and overdispersed discrete data in a hierarchical framework. This methodology was first introduced by Nakagawa and Osaki (1975, IEEE Transactions on Reliability, ... -
Tuning protein frameworks via auxiliary supramolecular interactions
(American Chemical Society, 2019-09-06)Protein crystals with their precise, periodic array of functional building blocks have potential applications in biomaterials, sensing, and catalysis. This paper describes how a highly porous crystalline framework of a ... -
Models for overdispersed data in entomology
(Springer, Cham, 2014-09-17)Entomological data are often overdispersed, characterised by a larger variance than assumed by simple standard models. It is important to model overdispersion properly in order to avoid incorrect and misleading inferences. ... -
Biological applications of knowledge graph embedding models
(Oxford University Press (OUP), 2020-02-17)Complex biological systems are traditionally modelled as graphs of interconnected biological entities. These graphs, i.e. biological knowledge graphs, are then processed using graph exploratory approaches to perform different ... -
Long-term human impact and environmental change in mid-western Ireland, with particular reference to Céide Fields – an overview
(Copernicus Publications on behalf of the Deutsche Quartärvereinigung (DEUQUA), 2020-02-11)This paper presents new palaeoecological data from north Co. Mayo, western Ireland, and reviews published data with a view to achieving a better understanding of the timing and nature of early farming in the region, its ... -
Calixarene-mediated assembly of a small antifungal protein
(International Union of Crystallography, 2019-02-05)Synthetic macrocycles such as calixarenes and cucurbiturils are increasingly applied as mediators of protein assembly and crystallization. The macrocycle can facilitate assembly by providing a surface on which two or more ... -
Influenza vaccine uptake and attitudes of healthcare workers in Ireland
(Oxford University Press (OUP), 2019-11-05)Influenza vaccination uptake by Irish healthcare workers remains sub-optimal despite local initiatives to increase it. To investigate hospital workers' attitudes to influenza vaccination and how this influenced their ... -
Mentoring: výchova k profesionálně vedenému dobrovolnictví
(Portál, 2010)The book, written in Czech language, provides a through rough literature review on the knowledge and viable theoretical approaches to the mentoring interventions and assessment of the quality of mentoring programmes through ... -
Implications of histone H2AX abundance in breast cancer
(NUI Galway, 2019-12-09)Histones are responsible for the packaging of DNA into a eukaryotic cell nucleus, and the H2A variant H2AX plays an important role in the DNA damage response (DDR). The phosphorylated form of H2AX, known as γH2AX, has been ... -
Graph-based diffusion methods for node classification and link prediction
(NUI Galway, 2020-02-13)Graphs are common representation tools to organize information from heterogeneous sources. They have been applied in various domains such as the scientific, engineering, political, and business sectors. The large volume ... -
The evolution of behaviours in swarms of robots
(NUI Galway, 2019-12-09)Evolutionary swarm robotics uses evolutionary computational techniques to synthesise behaviours for a group of autonomous robots. In a swarm of robots, the collective behaviour of the robots results from the local interactions ... -
Sheltered work and intellectual disability equality: Can the UN Convention on the Rights of Persons with Disabilities tackle this form of segregation?
(NUI Galway, 2020-02-13)This thesis is a theoretical study that addresses the enduring segregation of people with intellectual disabilities in sheltered work environments. Having identified that many people with intellectual disabilities remain ... -
'The Problem of the Mentally Handicapped': statutory policy, voluntary provision and intellectual disability in Ireland, 1947-84
(NUI Galway, 2020-02-12)This thesis is a historical investigation of how the state and voluntary sector responded to intellectual disability in Ireland, from the foundation of the Department of Health in 1947 to the 1984 Towards a Full Life Green ... -
Synthesis and evaluation of multivalent ligands for macrophage galactose C-type lectin. Development of new chemical tools for immunological research and structural investigation of the lectin with GalNAc and derivatives
(NUI Galway, 2019-09-30)Synthetic chemistry can provide powerful tools to explore the correlation between an antigen’s chemical structure and the type of immune response triggered. This thesis work has focused on the design, synthesis and ... -
Identification and characterisation of germline variants in an Irish cohort with breast cancer
(NUI Galway, 2020-02-10)Breast cancer is the most common female malignancy worldwide, and the second most common cause of cancer-related deaths in women. Twin studies estimate that up to one third of breast cancers are the result of hereditary ... -
Collaborative learning, role play and case study: Pedagogical pathways to professionalism and ethics in school placement
(Learning Connections UCC, 2019-12-05)Teachers are moral agents. Acting professionally in loco parentis teachers have a legal and moral duty of care to students (DES, 2017). Moreover, they can be regarded as moral role models (Bergen, 2006; Lumpkin, 2013). ... -
Towards a common standard of protection of the right to housing in Europe through the charter of fundamental rights
(Wiley, 2019-12-17)The trend towards the financialisation of housing since the 1980s and the global financial crisis exposed a dramatic lacuna in the legal protection of the right to housing. Yet, the right to housing features not only in ...