Now showing items 1-4 of 4
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
(Springer Nature, 2015-03-09)
Genome-wide association studies (GWAS) and large-scale replication studies have identified common variants in 79 loci associated with breast cancer, explaining similar to 14% of the familial risk of the disease. To identify ...
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the enigma consortium
(Springer Nature, 2015-06-02)
The profile of brain structural abnormalities in schizophrenia is still not fully understood, despite decades of research using brain scans. To validate a prospective meta-analysis approach to analyzing multicenter ...
Awareness and uptake of family screening in patients diagnosed with colorectal cancer at a young age
(Hindawi Limited, 2015-01-01)
Background. One-fifth of people who develop colorectal cancer (CRC) have a first-degree relative (FDR) also affected. There is a large disparity in guidelines for screening of relatives of patients with CRC. Herein we ...
Identification of novel genetic markers of breast cancer survival
(Oxford University Press (OUP), 2015-04-18)
Background: Survival after a diagnosis of breast cancer varies considerably between patients, and some of this variation may be because of germline genetic variation. We aimed to identify genetic markers associated with ...